InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en...
Acquired myasthenia gravis (MGA) is an immnunomediated disease that affects the canine species, caused by the presence of antibodies against postsynaptic nicotinic choloreceptors and the consequent interference in the neuromuscular transmission of voluntary muscles. Six canines with ocular alteratio...
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| Formato: | Artículo publishedVersion |
| Lenguaje: | Español |
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Universidad de Buenos Aires. Facultad de Ciencias Veterinarias.
2020
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| Acceso en línea: | http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_3710 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_3710.dir/3710.PDF |
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I28-R145-HWA_3710 |
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I28-R145-HWA_37102024-11-05 InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... Acquired myasthenia gravis (MGA) is an immnunomediated disease that affects the canine species, caused by the presence of antibodies against postsynaptic nicotinic choloreceptors and the consequent interference in the neuromuscular transmission of voluntary muscles. Six canines with ocular alterations and clinical signology compatible with MGA from the Hospital School of the Faculty of Veterinary Sciences of the University of Buenos Aires were diagnosed by the presence of antibodies against serum acetylcholine receptor (ACRA). These animals showed visual deficits, with P100 waves of diminished amplitude values in evoked potentials (VEP). They were treated with 0.5 mg / kg pyridostigmine bromide orally every 12 h, for 30 days and after this period, they were re-evaluated. The VEP obtained after treatment showed that 80% (5/6) of the animals increased the amplitude of the P100 wave. Visual evoked potentials offer a non-invasive method that identifies the central effects of AMS and its therapeutic evolution. Fil: Suraniti, A.P. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Hospital Escuela de Medicina Veterinaria. Unidad de Neurología. Buenos Aires, Argentina Fil: López, C.M. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Salud Pública. Buenos Aires, Argentina Fil: Gilardoni, L.R. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Semiología. Buenos Aires, Argentina Fil: Gilardoni, L.R. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Inmunología. Buenos Aires, Argentina Fil: Berttoti, A. Hospital Alemán. Buenos Aires, Argentina Fil: Mundo, S.L. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Inmunología. Buenos Aires, Argentina Suraniti, A.P. López, C.M. Gilardoni, L.R. Berttoti, A. Mundo, S.L. 2020 La miastenia gravis adquirida (MGA) es una enfermedad inmnunomediada que afecta a la especie canina, causada por la presencia de anticuerpos contra los colinoreceptores nicotínicos postsinápticos y la consiguiente interferencia en la transmisión neuromuscular de los músculos voluntarios. Seis caninos con alteraciones oculares y signología clínica compatible con MGA provenientes del Hospital Escuela de la Facultad de Ciencias Veterinarias de la Universidad de Buenos Aires fueron diagnosticados por la presencia de anticuerpos anti receptor de acetilcolina en suero (ACRA). Estos animales mostraron déficits visuales, con ondas P100 de valores de amplitud disminuidas en los potenciales evocados (PEV). Se los trató con Bromuro de piridostigmina 0,5 mg/kg vía oral cada 12 h, durante 30 días y luego de este período, se re-evaluaron. Los PEV obtenidos luego del tratamiento mostraron que el 80% (5/6) de los animales incrementaron la amplitud de la onda P100. Los potenciales evocados visuales ofrecen un método no invasivo que permite identificar los efectos centrales de la MGA y su evolución terapéutica.\n application/pdf 1514-6634 (impreso) 1668-3498 (en línea) Enfermedad neuromuscular Diagnostico Caninos Neuromuscular disease Diagnosis Canine spa Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ InVet, vol. 22, nº1 Utilización de potenciales evocados visuales para el diagnóstico y evolución de Miastenia gravis adquirida en caninos Use of visual evoked potentials for the diagnosis and evolution of acquired Myasthenia gravis in canines info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_3710 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_3710.dir/3710.PDF |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-145 |
| collection |
Repositorio Digital de la Universidad de Buenos Aires (UBA) |
| language |
Español |
| orig_language_str_mv |
spa |
| topic |
Enfermedad neuromuscular Diagnostico Caninos Neuromuscular disease Diagnosis Canine |
| spellingShingle |
Enfermedad neuromuscular Diagnostico Caninos Neuromuscular disease Diagnosis Canine Suraniti, A.P. López, C.M. Gilardoni, L.R. Berttoti, A. Mundo, S.L. InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| topic_facet |
Enfermedad neuromuscular Diagnostico Caninos Neuromuscular disease Diagnosis Canine |
| description |
Acquired myasthenia gravis (MGA) is an immnunomediated disease that affects the canine species, caused by the presence of antibodies against postsynaptic nicotinic choloreceptors and the consequent interference in the neuromuscular transmission of voluntary muscles. Six canines with ocular alterations and clinical signology compatible with MGA from the Hospital School of the Faculty of Veterinary Sciences of the University of Buenos Aires were diagnosed by the presence of antibodies against serum acetylcholine receptor (ACRA). These animals showed visual deficits, with P100 waves of diminished amplitude values in evoked potentials (VEP). They were treated with 0.5 mg / kg pyridostigmine bromide orally every 12 h, for 30 days and after this period, they were re-evaluated. The VEP obtained after treatment showed that 80% (5/6) of the animals increased the amplitude of the P100 wave. Visual evoked potentials offer a non-invasive method that identifies the central effects of AMS and its therapeutic evolution. |
| format |
Artículo Artículo publishedVersion |
| author |
Suraniti, A.P. López, C.M. Gilardoni, L.R. Berttoti, A. Mundo, S.L. |
| author_facet |
Suraniti, A.P. López, C.M. Gilardoni, L.R. Berttoti, A. Mundo, S.L. |
| author_sort |
Suraniti, A.P. |
| title |
InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| title_short |
InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| title_full |
InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| title_fullStr |
InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| title_full_unstemmed |
InVet 2020, 22 (1): 1-10 ISSN 1514-6634 (impreso) ISSN 1668-3498 (en... |
| title_sort |
invet 2020, 22 (1): 1-10 issn 1514-6634 (impreso) issn 1668-3498 (en... |
| publisher |
Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. |
| publishDate |
2020 |
| url |
http://repositoriouba.sisbi.uba.ar/gsdl/cgi-bin/library.cgi?a=d&c=pveterinaria/invet&cl=CL1&d=HWA_3710 https://repositoriouba.sisbi.uba.ar/gsdl/collect/pveterinaria/invet/index/assoc/HWA_3710.dir/3710.PDF |
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