Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease
Cystic ovarian disease (COD) is one of the most frequent reproductive disorders in dairy cows. Their development is associated with an imbalance in the hypothalamus-hypophyseal-gonadal axis in which endocrine factors, including insulin like growth factor (IGF) system, are involved in follicular deve...
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Universidad Nacional del Litoral
2016
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I26-R133-article-54892023-09-15T10:27:47Z Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease Participación del sistema IGF en la patogenia de la enfermedad quística bovina RODRIGUEZ, Fernanda M. SALVETTI, Natalia R. ORTEGA, Hugo H. REY, Florencia insuline like growth factor system cystic ovarian disease cow insulin like growth factor system enfermedad quística bovina vaca Cystic ovarian disease (COD) is one of the most frequent reproductive disorders in dairy cows. Their development is associated with an imbalance in the hypothalamus-hypophyseal-gonadal axis in which endocrine factors, including insulin like growth factor (IGF) system, are involved in follicular development, cell differentiation and secretion ovarian hormones. Considering that the IGF system is an important regulator of the follicular growth and functionality, we have evaluated the involvement of members of the IGF system in the COD development. Alterations in different components of the IGF system could modify the normal ovarian function and participate in the development of the COD in cattle. La enfermedad quística ovárica (COD) es una de las principales causas de falla reproductiva y de infertilidad, y constituye uno de los de los trastornos reproductivos más frecuentes en vacas lecheras de alta producción. El desarrollo de esta enfermedad está asociado a un desequilibrio en el eje hipotalámico-hipofisario-gonadal en el cual factores endocrinos, entre ellos el sistema de factores de crecimiento análogos a insulina (IGF), participan en el desarrollo folicular, diferenciación celular y la secreción de hormonas ováricas. Considerando al sistema IGF como un importante regulador del crecimiento y funcionalidad folicular, evaluamos la participación de componentes del sistema IGF en el desarrollo de la COD. Las alteraciones en diferentes componentes del sistema IGF que podrían afectar al normal funcionamiento del ovario participando en el desarrollo de la COD en bovinos. Universidad Nacional del Litoral 2016-04-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Revisión Review application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/5489 10.14409/favecv.v14i1/2.5489 FAVE Sección Ciencias Veterinarias; Vol. 14 Núm. 1/2 (2015): FAVE Sección Ciencias Veterinarias; 28-37 FAVE Sección Ciencias Veterinarias; Vol. 14 No. 1/2 (2015): FAVE Sección Ciencias Veterinarias; 28-37 FAVE Sección Ciencias Veterinarias; v. 14 n. 1/2 (2015): FAVE Sección Ciencias Veterinarias; 28-37 2362-5589 1666-938X 10.14409/favecv.v14i1/2 spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/5489/8201 |
institution |
Universidad Nacional del Litoral |
institution_str |
I-26 |
repository_str |
R-133 |
container_title_str |
Biblioteca Virtual - Publicaciones (UNL) |
language |
Español |
format |
Artículo revista |
topic |
insuline like growth factor system cystic ovarian disease cow insulin like growth factor system enfermedad quística bovina vaca |
spellingShingle |
insuline like growth factor system cystic ovarian disease cow insulin like growth factor system enfermedad quística bovina vaca RODRIGUEZ, Fernanda M. SALVETTI, Natalia R. ORTEGA, Hugo H. REY, Florencia Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
topic_facet |
insuline like growth factor system cystic ovarian disease cow insulin like growth factor system enfermedad quística bovina vaca |
author |
RODRIGUEZ, Fernanda M. SALVETTI, Natalia R. ORTEGA, Hugo H. REY, Florencia |
author_facet |
RODRIGUEZ, Fernanda M. SALVETTI, Natalia R. ORTEGA, Hugo H. REY, Florencia |
author_sort |
RODRIGUEZ, Fernanda M. |
title |
Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
title_short |
Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
title_full |
Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
title_fullStr |
Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
title_full_unstemmed |
Participation of the IGF system in the pathogenesis of bovine cystic ovarian disease |
title_sort |
participation of the igf system in the pathogenesis of bovine cystic ovarian disease |
description |
Cystic ovarian disease (COD) is one of the most frequent reproductive disorders in dairy cows. Their development is associated with an imbalance in the hypothalamus-hypophyseal-gonadal axis in which endocrine factors, including insulin like growth factor (IGF) system, are involved in follicular development, cell differentiation and secretion ovarian hormones. Considering that the IGF system is an important regulator of the follicular growth and functionality, we have evaluated the involvement of members of the IGF system in the COD development. Alterations in different components of the IGF system could modify the normal ovarian function and participate in the development of the COD in cattle. |
publisher |
Universidad Nacional del Litoral |
publishDate |
2016 |
url |
https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/5489 |
work_keys_str_mv |
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first_indexed |
2023-07-05T23:06:50Z |
last_indexed |
2024-08-13T20:38:21Z |
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