COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE

The aim of this study was to propose an alternative statistic treatment for the results obtained by testing the in vitro efficacy of ivermectin (IVM) against R. microplus using the larval immersion test in order to detect the emergence of resistant strains. The statistical analysis of the results ob...

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Autor principal: Torrents, J
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2021
Materias:
Rhipicephalus microplus, larval immersion test, statistical analysis
Rhipicephalus microplus, test de inmersión de larvas, análisis estadístico
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10954
Aporte de:
Biblioteca Virtual - Publicaciones (UNL) de Universidad Nacional del Litoral
id I26-R133-article-10954
record_format ojs
spelling I26-R133-article-109542023-09-15T10:33:20Z COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE COMPARACIÓN ENTRE EL MODELO PROBIT Y EL MODELO DE HILL PARA DETERMINAR LA EFICACIA DE IVERMECTINA SOBRE LARVAS DE Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) MEDIANTE LA TÉCNICA DE INMERSIÓN. Torrents, J Rhipicephalus microplus, larval immersion test, statistical analysis Rhipicephalus microplus, test de inmersión de larvas, análisis estadístico The aim of this study was to propose an alternative statistic treatment for the results obtained by testing the in vitro efficacy of ivermectin (IVM) against R. microplus using the larval immersion test in order to detect the emergence of resistant strains. The statistical analysis of the results obtained by this technique is standardized by the FAO who proposes the use of the Probit model. However there are alternative mathematical models that allow a more precise analysis of experimental data generating more information as nonlinear logistic equation, also called the Hill model. The results of the IVM efficacy against a sensible strain of R. microplus were analysed whit both model. A comparison between the results obtained with PROBIT and Hill model showed that the last one was able to make a more precise fit of the experimental data, generating more information about small IVM concentrations.  The C50 (13.58 ppm) obtained with Probit model result smaller than the obtained with the Hill model (14.24 ppm), however the C90, C99 and the discriminant dose (19.31 ppm, 25.74 ppm, 51.48 ppm) obtained with de Hill model were bigger than the obtained with the Probit model (17.50 ppm, 21.98 ppm, 43.96 ppm). Universidad Nacional del Litoral 2021-12-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10954 10.14409/favecv.v19isuplemento.10954 FAVE Sección Ciencias Veterinarias; Vol. 19 Núm. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; Vol. 19 No. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; v. 19 n. suplemento (2021): FAVE Sección Ciencias Veterinarias 2362-5589 1666-938X 10.14409/favecv.v19isuplemento spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10954/14966 Derechos de autor 2021 J Torrents
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic Rhipicephalus microplus, larval immersion test, statistical analysis
Rhipicephalus microplus, test de inmersión de larvas, análisis estadístico
spellingShingle Rhipicephalus microplus, larval immersion test, statistical analysis
Rhipicephalus microplus, test de inmersión de larvas, análisis estadístico
Torrents, J
COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
topic_facet Rhipicephalus microplus, larval immersion test, statistical analysis
Rhipicephalus microplus, test de inmersión de larvas, análisis estadístico
author Torrents, J
author_facet Torrents, J
author_sort Torrents, J
title COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
title_short COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
title_full COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
title_fullStr COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
title_full_unstemmed COMPARISON BETWEEN THE PROBIT MODEL AND THE HILL MODEL TO DETERMINE THE EFFICACY OF IVERMECTIN ON Rhipicephalus (Boophilus) microplus (ACARI, IXODIDA: IXODIDAE) WITH LARVAL IMMERSION TECHNIQUE
title_sort comparison between the probit model and the hill model to determine the efficacy of ivermectin on rhipicephalus (boophilus) microplus (acari, ixodida: ixodidae) with larval immersion technique
description The aim of this study was to propose an alternative statistic treatment for the results obtained by testing the in vitro efficacy of ivermectin (IVM) against R. microplus using the larval immersion test in order to detect the emergence of resistant strains. The statistical analysis of the results obtained by this technique is standardized by the FAO who proposes the use of the Probit model. However there are alternative mathematical models that allow a more precise analysis of experimental data generating more information as nonlinear logistic equation, also called the Hill model. The results of the IVM efficacy against a sensible strain of R. microplus were analysed whit both model. A comparison between the results obtained with PROBIT and Hill model showed that the last one was able to make a more precise fit of the experimental data, generating more information about small IVM concentrations.  The C50 (13.58 ppm) obtained with Probit model result smaller than the obtained with the Hill model (14.24 ppm), however the C90, C99 and the discriminant dose (19.31 ppm, 25.74 ppm, 51.48 ppm) obtained with de Hill model were bigger than the obtained with the Probit model (17.50 ppm, 21.98 ppm, 43.96 ppm).
publisher Universidad Nacional del Litoral
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10954
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first_indexed 2023-07-05T23:06:10Z
last_indexed 2024-08-13T20:37:37Z
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