SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL

The aim of this study was to obtain pharmacodynamics parameters to detect resistance or susceptibility of R. microplus strains to ivermectin (IVM). Two larvae samples; a susceptible strain (S) and field isolation (T) were treated with increasing concentrations of IVM using the larvae immersion techn...

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Autor principal: Torrents, J
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2021
Materias:
Rhipicephalus microplus, larval immersion test, ivermectin, Hill model.
Rhipicephalus microplus, test de inmersión de larvas, ivermectina, modelo de Hill.
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10943
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Biblioteca Virtual - Publicaciones (UNL) de Universidad Nacional del Litoral
id I26-R133-article-10943
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spelling I26-R133-article-109432023-09-15T10:33:20Z SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL SENSIBILIDAD DE LA GARRAPATA COMÚN DEL BOVINO Rhipicephalus (Boophilus) microplus A IVERMECTINA ESTIMADA CON EL MODELO SIGMOIDEO DE RESPUESTA MÁXIMA O DE HILL Torrents, J Rhipicephalus microplus, larval immersion test, ivermectin, Hill model. Rhipicephalus microplus, test de inmersión de larvas, ivermectina, modelo de Hill. The aim of this study was to obtain pharmacodynamics parameters to detect resistance or susceptibility of R. microplus strains to ivermectin (IVM). Two larvae samples; a susceptible strain (S) and field isolation (T) were treated with increasing concentrations of IVM using the larvae immersion technique the efficacy values measured at 24 hours were analysed with the sigmoidal maximum response so called Hill model as statistical analysis. The results obtained showed that the IVM have an all or nothing response represented by the Hill coefficient value >1 in both samples. Additionally, a low concentration effect was observed as E0 de 12.83% (S) and 9.91% (T). The field isolation larvae were susceptible to IVM in comparison with the susceptible strain by the resistance ratio (RR) which in one case was not significantly greater that one (RR50= 0.756 and RR90=1.009). Universidad Nacional del Litoral 2021-12-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10943 10.14409/favecv.v19isuplemento.10943 FAVE Sección Ciencias Veterinarias; Vol. 19 Núm. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; Vol. 19 No. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; v. 19 n. suplemento (2021): FAVE Sección Ciencias Veterinarias 2362-5589 1666-938X 10.14409/favecv.v19isuplemento spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10943/14962 Derechos de autor 2021 J Torrents
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic Rhipicephalus microplus, larval immersion test, ivermectin, Hill model.
Rhipicephalus microplus, test de inmersión de larvas, ivermectina, modelo de Hill.
spellingShingle Rhipicephalus microplus, larval immersion test, ivermectin, Hill model.
Rhipicephalus microplus, test de inmersión de larvas, ivermectina, modelo de Hill.
Torrents, J
SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
topic_facet Rhipicephalus microplus, larval immersion test, ivermectin, Hill model.
Rhipicephalus microplus, test de inmersión de larvas, ivermectina, modelo de Hill.
author Torrents, J
author_facet Torrents, J
author_sort Torrents, J
title SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
title_short SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
title_full SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
title_fullStr SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
title_full_unstemmed SENSITIVITY OF THE COMMON BOVINE TICK Rhipicephalus (Boophilus) microplus TO IVERMECTIN ESTIMATED WITH THE SIGMOIDAL MAXIMUM RESPONSE MODEL OR HILL MODEL
title_sort sensitivity of the common bovine tick rhipicephalus (boophilus) microplus to ivermectin estimated with the sigmoidal maximum response model or hill model
description The aim of this study was to obtain pharmacodynamics parameters to detect resistance or susceptibility of R. microplus strains to ivermectin (IVM). Two larvae samples; a susceptible strain (S) and field isolation (T) were treated with increasing concentrations of IVM using the larvae immersion technique the efficacy values measured at 24 hours were analysed with the sigmoidal maximum response so called Hill model as statistical analysis. The results obtained showed that the IVM have an all or nothing response represented by the Hill coefficient value >1 in both samples. Additionally, a low concentration effect was observed as E0 de 12.83% (S) and 9.91% (T). The field isolation larvae were susceptible to IVM in comparison with the susceptible strain by the resistance ratio (RR) which in one case was not significantly greater that one (RR50= 0.756 and RR90=1.009).
publisher Universidad Nacional del Litoral
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10943
work_keys_str_mv AT torrentsj sensitivityofthecommonbovinetickrhipicephalusboophilusmicroplustoivermectinestimatedwiththesigmoidalmaximumresponsemodelorhillmodel
AT torrentsj sensibilidaddelagarrapatacomundelbovinorhipicephalusboophilusmicroplusaivermectinaestimadaconelmodelosigmoideoderespuestamaximaodehill
first_indexed 2023-07-05T23:06:09Z
last_indexed 2024-08-13T20:37:36Z
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