DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS

Ulcerative dermatitis (UD) is a common and spontaneous condition in mice. The disease is characterized by a pruritic skin lesion, pain and a progressive evolution that often results in ulcerations. Sex, environmental conditions, dietary variation, chronic inflammation, barbering and follicular dystr...

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Autor principal: Sacco, S C
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2021
Materias:
Ulcerative dermatitis; mouse; histopathology
Dermatitis ulcerativa; ratón; histopatología
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10939
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Biblioteca Virtual - Publicaciones (UNL) de Universidad Nacional del Litoral
id I26-R133-article-10939
record_format ojs
spelling I26-R133-article-109392021-12-06T15:42:58Z DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS Ulcerative dermatitis in balbc/cmedc mice: report of 3 cases. Sacco, S C Ulcerative dermatitis; mouse; histopathology Dermatitis ulcerativa; ratón; histopatología Ulcerative dermatitis (UD) is a common and spontaneous condition in mice. The disease is characterized by a pruritic skin lesion, pain and a progressive evolution that often results in ulcerations. Sex, environmental conditions, dietary variation, chronic inflammation, barbering and follicular dystrophy are some predisposing factors for the clinical disease development. The aim of this study was report 3 cases of UD in BALBc/Cmedc mice from Center for Comparative Medicine, gross and histopathological lesions were described, and a review about relevance of UD in laboratory mice was made. These cases were characterized by dermatitis, ulcerative and proliferative, chronic, moderate, with neutrophils, hemorrhage and a serocellular crust. Although initial lesions may be mild, lesions in UD typically are unresponsive to treatment and euthanasia is often warranted in severe cases. This is the reason why UD is an important clinical issue that often affects biomedical research by causing problems in mice health and premature removal of animal from laboratory studies. Universidad Nacional del Litoral 2021-12-06 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10939 10.14409/favecv.v19isuplemento.10939 FAVE Sección Ciencias Veterinarias; Vol. 19 Núm. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; Vol. 19 No. suplemento (2021): FAVE Sección Ciencias Veterinarias FAVE Sección Ciencias Veterinarias; v. 19 n. suplemento (2021): FAVE Sección Ciencias Veterinarias 2362-5589 1666-938X 10.14409/favecv.v19isuplemento spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10939/14958 Derechos de autor 2021 S C Sacco
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic Ulcerative dermatitis; mouse; histopathology
Dermatitis ulcerativa; ratón; histopatología
spellingShingle Ulcerative dermatitis; mouse; histopathology
Dermatitis ulcerativa; ratón; histopatología
Sacco, S C
DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
topic_facet Ulcerative dermatitis; mouse; histopathology
Dermatitis ulcerativa; ratón; histopatología
author Sacco, S C
author_facet Sacco, S C
author_sort Sacco, S C
title DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
title_short DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
title_full DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
title_fullStr DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
title_full_unstemmed DERMATITIS ULCERATIVA EN RATONES BALB/c Cmedc: REPORTE DE 3 CASOS
title_sort dermatitis ulcerativa en ratones balb/c cmedc: reporte de 3 casos
description Ulcerative dermatitis (UD) is a common and spontaneous condition in mice. The disease is characterized by a pruritic skin lesion, pain and a progressive evolution that often results in ulcerations. Sex, environmental conditions, dietary variation, chronic inflammation, barbering and follicular dystrophy are some predisposing factors for the clinical disease development. The aim of this study was report 3 cases of UD in BALBc/Cmedc mice from Center for Comparative Medicine, gross and histopathological lesions were described, and a review about relevance of UD in laboratory mice was made. These cases were characterized by dermatitis, ulcerative and proliferative, chronic, moderate, with neutrophils, hemorrhage and a serocellular crust. Although initial lesions may be mild, lesions in UD typically are unresponsive to treatment and euthanasia is often warranted in severe cases. This is the reason why UD is an important clinical issue that often affects biomedical research by causing problems in mice health and premature removal of animal from laboratory studies.
publisher Universidad Nacional del Litoral
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FAVEveterinaria/article/view/10939
work_keys_str_mv AT saccosc dermatitisulcerativaenratonesbalbccmedcreportede3casos
AT saccosc ulcerativedermatitisinbalbccmedcmicereportof3cases
first_indexed 2023-07-05T23:06:08Z
last_indexed 2023-07-05T23:06:08Z
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