Meningitis and septicemia due to Listeria monocytogenes

Listeria monocytogenes (Lm) is a gram-positive bacillus considered opportunistic. It particularly affects pregnant women, newborns, the elderly and  immunocompromised and can cause a wide range  of clinical manifestations ranging from  febrile syndrome to a severe invasive...

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Autores principales: Taborda, R. P., Mendosa, M. A., Ramos, C., Manias, V., Lorenz, R., Cristobal, S., Macagno, D., Nardin, M. E.
Formato: Artículo revista
Lenguaje:Español
Publicado: Facultad de Bioquímica y Ciencias Biológicas (UNL) 2021
Materias:
Listeria monocytogenes
meningitis
bacteremia
Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FABICIB/article/view/10867
Aporte de:
Biblioteca Virtual - Publicaciones (UNL) de Universidad Nacional del Litoral
id I26-R133-article-10867
record_format ojs
spelling I26-R133-article-108672021-12-21T12:48:41Z Meningitis and septicemia due to Listeria monocytogenes  Meningitis y septicemia por Listeria monocytogenes Taborda, R. P. Mendosa, M. A. Ramos, C. Manias, V. Lorenz, R. Cristobal, S. Macagno, D. Nardin, M. E. Listeria monocytogenes meningitis bacteremia Listeria monocytogenes meningitis bacteremia Listeria monocytogenes (Lm) is a gram-positive bacillus considered opportunistic. It particularly affects pregnant women, newborns, the elderly and  immunocompromised and can cause a wide range  of clinical manifestations ranging from  febrile syndrome to a severe invasive disease that includes bacteremia, sepsis, meningitis and meningoencephalitis. We present the case of an adult male patient with a history of hypertension, psoriasis, cirrhosis and insulin-dependent type II diabetes who i was admitted to intensive care at Hospital J. m. Cullen with feverish symptoms, asthenia, psychomotor excitement, and temporal-spatial disorientation associated with  neck stiffness. Blood, urine, and CSF samples were taken for culture, and empirical treatment with ceftriaxone and vancpmycin was indicated..In the Gram staining of the CSF and blood culture samples, the presence of positive bacilli was observed. In the cultures they developed small and greyish colonies that were identified by automated method Phoenix 100 (BD) and conventional phenotypic test such as Lm. Against this result the medication was rotated to ampicillin and gentamicin. . The patient evolved favorably and once  treatment was completed, he was discharged without sequelae. It is important to perform a thorough anamnesis and suspect rare bacteria such as Lm, which can cause treatment failures whit the initial empirical therapy. Key words: Listeria monocytogenes, meningitis, bacteremia. Listeria monocytogenes (Lm) es una bacteria gram positiva considerada oportunista. Afecta particularmente a embarazadas, neonatos, ancianos e inmunocomprometidos y puede ocasionar un amplio espectro de manifestaciones clínicas que van desde un síndrome febril a una enfermedad invasiva grave que incluye bacteriemias, sepsis, meningitis y meningoencefalitis.  Se presenta el caso de un paciente adulto masculino con antecedentes de hipertensión, psoriasis, cirrosis y diabetes tipo II insulinodependiente, que ingresó a terapia intensiva del Hospital J. M. Cullen con cuadro febril, astenia, excitación psicomotriz y desorientación temporo espacial asociada a rigidez de nuca.   Se tomaron muestras de sangre, orina y LCR para cultivo,  y se le indicó tratamiento empírico con ceftriaxona y vancomicina. En la coloración de Gram del LCR y de las muestras de hemocultivo se observó la presencia de bacilos positivos. En los cultivos se desarrollaron colonias pequeñas y grisáceas que se identificaron mediante método automatizado Phoenix 100 (BD) y pruebas fenotípicas convencionales como Lmq. Frente a este resultado se rotó la medicación a ampicilina y gentamicina. El paciente evolucionó  favorablemente y una vez finalizado el tratamiento fue dado de alta sin secuelas. Se destaca la importancia de realizar una anamnesis exhaustiva y sospechar bacterias poco frecuentes como Listeria monocytogenes, que pueden originar fallas de tratamiento con la terapia empírica inicial. Facultad de Bioquímica y Ciencias Biológicas (UNL) 2021-11-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FABICIB/article/view/10867 10.14409/fabicib.v25i0.10867 FABICIB; Vol. 25 (2021): FABICIB FABICIB; Vol. 25 (2021): FABICIB 2362-5546 0329-5559 10.14409/fabicib.v25i0 spa https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FABICIB/article/view/10867/14649 Derechos de autor 2021 FABICIB
institution Universidad Nacional del Litoral
institution_str I-26
repository_str R-133
container_title_str Biblioteca Virtual - Publicaciones (UNL)
language Español
format Artículo revista
topic Listeria monocytogenes
meningitis
bacteremia
Listeria monocytogenes
meningitis
bacteremia
spellingShingle Listeria monocytogenes
meningitis
bacteremia
Listeria monocytogenes
meningitis
bacteremia
Taborda, R. P.
Mendosa, M. A.
Ramos, C.
Manias, V.
Lorenz, R.
Cristobal, S.
Macagno, D.
Nardin, M. E.
Meningitis and septicemia due to Listeria monocytogenes
topic_facet Listeria monocytogenes
meningitis
bacteremia
Listeria monocytogenes
meningitis
bacteremia
author Taborda, R. P.
Mendosa, M. A.
Ramos, C.
Manias, V.
Lorenz, R.
Cristobal, S.
Macagno, D.
Nardin, M. E.
author_facet Taborda, R. P.
Mendosa, M. A.
Ramos, C.
Manias, V.
Lorenz, R.
Cristobal, S.
Macagno, D.
Nardin, M. E.
author_sort Taborda, R. P.
title Meningitis and septicemia due to Listeria monocytogenes
title_short Meningitis and septicemia due to Listeria monocytogenes
title_full Meningitis and septicemia due to Listeria monocytogenes
title_fullStr Meningitis and septicemia due to Listeria monocytogenes
title_full_unstemmed Meningitis and septicemia due to Listeria monocytogenes
title_sort meningitis and septicemia due to listeria monocytogenes
description Listeria monocytogenes (Lm) is a gram-positive bacillus considered opportunistic. It particularly affects pregnant women, newborns, the elderly and  immunocompromised and can cause a wide range  of clinical manifestations ranging from  febrile syndrome to a severe invasive disease that includes bacteremia, sepsis, meningitis and meningoencephalitis. We present the case of an adult male patient with a history of hypertension, psoriasis, cirrhosis and insulin-dependent type II diabetes who i was admitted to intensive care at Hospital J. m. Cullen with feverish symptoms, asthenia, psychomotor excitement, and temporal-spatial disorientation associated with  neck stiffness. Blood, urine, and CSF samples were taken for culture, and empirical treatment with ceftriaxone and vancpmycin was indicated..In the Gram staining of the CSF and blood culture samples, the presence of positive bacilli was observed. In the cultures they developed small and greyish colonies that were identified by automated method Phoenix 100 (BD) and conventional phenotypic test such as Lm. Against this result the medication was rotated to ampicillin and gentamicin. . The patient evolved favorably and once  treatment was completed, he was discharged without sequelae. It is important to perform a thorough anamnesis and suspect rare bacteria such as Lm, which can cause treatment failures whit the initial empirical therapy. Key words: Listeria monocytogenes, meningitis, bacteremia.
publisher Facultad de Bioquímica y Ciencias Biológicas (UNL)
publishDate 2021
url https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/FABICIB/article/view/10867
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first_indexed 2023-07-05T23:01:46Z
last_indexed 2023-07-05T23:01:46Z
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