Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America

Pathogenic Escherichia coli are known to be a common cause of diarrheal disease and a frequently occurring bacterial infection in children and adults in Latin America. Despite the effort to combat diarrheal infections, the south of the American continent remains a hot spot for infections and sequela...

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Autores principales: Torres, Alfredo, Amaral, María Marta, Bentancor, Leticia Verónica, Galli, Lucía, Goldstein Raij, Jorge, Krüger, Alejandra, Rojas López, Maricarmen
Formato: Articulo Revision
Lenguaje:Inglés
Publicado: 2018
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/99334
https://ri.conicet.gov.ar/11336/88378
http://www.mdpi.com/2076-2607/6/4/100
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id I19-R120-10915-99334
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
Shiga toxin
STEC
Shiga toxin-producing E. coli
Enterohemorrhagic E. coli
Hemolytic uremic syndrome
Diarrhea
Vaccines
Therapeutics
Phages
spellingShingle Biología
Shiga toxin
STEC
Shiga toxin-producing E. coli
Enterohemorrhagic E. coli
Hemolytic uremic syndrome
Diarrhea
Vaccines
Therapeutics
Phages
Torres, Alfredo
Amaral, María Marta
Bentancor, Leticia Verónica
Galli, Lucía
Goldstein Raij, Jorge
Krüger, Alejandra
Rojas López, Maricarmen
Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
topic_facet Biología
Shiga toxin
STEC
Shiga toxin-producing E. coli
Enterohemorrhagic E. coli
Hemolytic uremic syndrome
Diarrhea
Vaccines
Therapeutics
Phages
description Pathogenic Escherichia coli are known to be a common cause of diarrheal disease and a frequently occurring bacterial infection in children and adults in Latin America. Despite the effort to combat diarrheal infections, the south of the American continent remains a hot spot for infections and sequelae associated with the acquisition of one category of pathogenic E. coli, the Shiga toxin-producing E. coli (STEC). This review will focus on an overview of the prevalence of different STEC serotypes in human, animals and food products, focusing on recent reports from Latin America outlining the recent research progress achieved in this region to combat disease and endemicity in affected countries and to improve understanding on emerging serotypes and their virulence factors. Furthermore, this review will highlight the progress done in vaccine development and treatment and will also discuss the effort of the Latin American investigators to respond to the thread of STEC infections by establishing a multidisciplinary network of experts that are addressing STEC-associated animal, human and environmental health issues, while trying to reduce human disease. Regardless of the significant scientific contributions to understand and combat STEC infections worldwide, many significant challenges still exist and this review has focus in the Latin American efforts as an example of what can be accomplished when multiple groups have a common goal.
format Articulo
Revision
author Torres, Alfredo
Amaral, María Marta
Bentancor, Leticia Verónica
Galli, Lucía
Goldstein Raij, Jorge
Krüger, Alejandra
Rojas López, Maricarmen
author_facet Torres, Alfredo
Amaral, María Marta
Bentancor, Leticia Verónica
Galli, Lucía
Goldstein Raij, Jorge
Krüger, Alejandra
Rojas López, Maricarmen
author_sort Torres, Alfredo
title Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
title_short Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
title_full Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
title_fullStr Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
title_full_unstemmed Recent Advances in Shiga Toxin-Producing Escherichia coli Research in Latin America
title_sort recent advances in shiga toxin-producing escherichia coli research in latin america
publishDate 2018
url http://sedici.unlp.edu.ar/handle/10915/99334
https://ri.conicet.gov.ar/11336/88378
http://www.mdpi.com/2076-2607/6/4/100
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