Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline

Three ternary complexes of sulfaquinoxaline (SQO-4-amino-N-2-quinoxalinylbenzenesulfonamide) or sulfamethazine (SMT-4-amino-N-(4,6-dimethylpyrimidin-2-yl)-benzenesulfonamide) with Cu(ii) or Ni(ii) and 2,2′-biquinoline (BQ) as an auxiliary ligand have been studied. Their structures have been determin...

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Detalles Bibliográficos
Autores principales:	Villa Pérez, Cristian, Cadavid Vargas, Juan Fernando, Di Virgilio, Ana Laura, Echeverría, Gustavo Alberto, Camí, Gerardo Enrique, Soria, Delia Beatriz
Formato:	Articulo Preprint
Lenguaje:	Inglés
Publicado:	2017
Materias:	Química Sulfaquinoxaline Sulfamethazine X-ray structure Hirshfeld surface calculations Intermolecular interactions Cytotoxicity
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/98897 https://ri.conicet.gov.ar/11336/93255 http://xlink.rsc.org/?DOI=C7NJ03624H
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-98897
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Química Sulfaquinoxaline Sulfamethazine X-ray structure Hirshfeld surface calculations Intermolecular interactions Cytotoxicity
spellingShingle	Química Sulfaquinoxaline Sulfamethazine X-ray structure Hirshfeld surface calculations Intermolecular interactions Cytotoxicity Villa Pérez, Cristian Cadavid Vargas, Juan Fernando Di Virgilio, Ana Laura Echeverría, Gustavo Alberto Camí, Gerardo Enrique Soria, Delia Beatriz Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
topic_facet	Química Sulfaquinoxaline Sulfamethazine X-ray structure Hirshfeld surface calculations Intermolecular interactions Cytotoxicity
description	Three ternary complexes of sulfaquinoxaline (SQO-4-amino-N-2-quinoxalinylbenzenesulfonamide) or sulfamethazine (SMT-4-amino-N-(4,6-dimethylpyrimidin-2-yl)-benzenesulfonamide) with Cu(ii) or Ni(ii) and 2,2′-biquinoline (BQ) as an auxiliary ligand have been studied. Their structures have been determined by single-crystal X-ray crystallography as Ni(SQO)2(BQ)·2H2O (I), Cu(SQO)(BQ)Cl·CH3OH (II) and Cu(SMT)(BQ)Cl (III). Compounds I and II crystallize in the triclinic space group P1 while complex III crystallizes in the monoclinic P21/c space group. The crystal lattice of all complexes is stabilized by the presence of diverse intermolecular interactions as verified by Hirshfeld surface analysis. Besides, electronic spectroscopies have also been used to characterize the compounds. The thermal behavior of the complexes was investigated by thermogravimetric and differential thermal analyses. Furthermore, the cytotoxic effect of the compounds has been tested against A549 (lung cancer) and MG-63 (human osteosarcoma) cell lines using the MTT methodology.
format	Articulo Preprint
author	Villa Pérez, Cristian Cadavid Vargas, Juan Fernando Di Virgilio, Ana Laura Echeverría, Gustavo Alberto Camí, Gerardo Enrique Soria, Delia Beatriz
author_facet	Villa Pérez, Cristian Cadavid Vargas, Juan Fernando Di Virgilio, Ana Laura Echeverría, Gustavo Alberto Camí, Gerardo Enrique Soria, Delia Beatriz
author_sort	Villa Pérez, Cristian
title	Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
title_short	Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
title_full	Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
title_fullStr	Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
title_full_unstemmed	Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
title_sort	crystal structure, hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline
publishDate	2017
url	http://sedici.unlp.edu.ar/handle/10915/98897 https://ri.conicet.gov.ar/11336/93255 http://xlink.rsc.org/?DOI=C7NJ03624H
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Crystal structure, Hirshfeld surface analysis, spectroscopic and biological studies on sulfamethazine and sulfaquinoxaline ternary complexes with 2,2′-biquinoline

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