Mechanism of action of drugs with activity against multicellular parasites

Parasiticides have been the most valuable weapons to combat parasites for almost half a century, constituting more than 50 % of veterinary pharmaceuticals and a good part of the products destined for human health. However, in many parts of the world, parasites develop resistance to these drugs, and...

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Autores principales: Giordani, C., Marín, Gustavo Horacio, Pérez, D., Soraci, Alejandro Luis, Errecalde, Jorge Oscar
Formato: Articulo
Lenguaje:Inglés
Publicado: 2017
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/98772
https://ri.conicet.gov.ar/11336/58597
https://www.zin.ru/journals/parazitologiya/content/2017/prz_2017_4_3_Giordani.pdf
Aporte de:
id I19-R120-10915-98772
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Mechanism of action, pharmacodynamics, antiparasitic agents
spellingShingle Ciencias Veterinarias
Mechanism of action, pharmacodynamics, antiparasitic agents
Giordani, C.
Marín, Gustavo Horacio
Pérez, D.
Soraci, Alejandro Luis
Errecalde, Jorge Oscar
Mechanism of action of drugs with activity against multicellular parasites
topic_facet Ciencias Veterinarias
Mechanism of action, pharmacodynamics, antiparasitic agents
description Parasiticides have been the most valuable weapons to combat parasites for almost half a century, constituting more than 50 % of veterinary pharmaceuticals and a good part of the products destined for human health. However, in many parts of the world, parasites develop resistance to these drugs, and it is now a major health problem. One way to avoid this inconvenience is the in-depth knowledge of its mechanisms of action, which will allow a more appropriate use. This work is a review of the different physiological aspects of parasite species and an explanation of the different mechanisms of action of antiparasitic agents. Once these drugs are ingested or absorbed by parasites the agents come into contact with the parasites structures, and according to the drug's properties it will define the antiparasitic activity either by altering tegument, carbohydrates, protein and lipid metabolism, or motility of the multicellular parasites.
format Articulo
Articulo
author Giordani, C.
Marín, Gustavo Horacio
Pérez, D.
Soraci, Alejandro Luis
Errecalde, Jorge Oscar
author_facet Giordani, C.
Marín, Gustavo Horacio
Pérez, D.
Soraci, Alejandro Luis
Errecalde, Jorge Oscar
author_sort Giordani, C.
title Mechanism of action of drugs with activity against multicellular parasites
title_short Mechanism of action of drugs with activity against multicellular parasites
title_full Mechanism of action of drugs with activity against multicellular parasites
title_fullStr Mechanism of action of drugs with activity against multicellular parasites
title_full_unstemmed Mechanism of action of drugs with activity against multicellular parasites
title_sort mechanism of action of drugs with activity against multicellular parasites
publishDate 2017
url http://sedici.unlp.edu.ar/handle/10915/98772
https://ri.conicet.gov.ar/11336/58597
https://www.zin.ru/journals/parazitologiya/content/2017/prz_2017_4_3_Giordani.pdf
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AT soracialejandroluis mechanismofactionofdrugswithactivityagainstmulticellularparasites
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