Mechanism of action of drugs with activity against multicellular parasites
Parasiticides have been the most valuable weapons to combat parasites for almost half a century, constituting more than 50 % of veterinary pharmaceuticals and a good part of the products destined for human health. However, in many parts of the world, parasites develop resistance to these drugs, and...
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Autores principales: | , , , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
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2017
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/98772 https://ri.conicet.gov.ar/11336/58597 https://www.zin.ru/journals/parazitologiya/content/2017/prz_2017_4_3_Giordani.pdf |
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I19-R120-10915-98772 |
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institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Ciencias Veterinarias Mechanism of action, pharmacodynamics, antiparasitic agents |
spellingShingle |
Ciencias Veterinarias Mechanism of action, pharmacodynamics, antiparasitic agents Giordani, C. Marín, Gustavo Horacio Pérez, D. Soraci, Alejandro Luis Errecalde, Jorge Oscar Mechanism of action of drugs with activity against multicellular parasites |
topic_facet |
Ciencias Veterinarias Mechanism of action, pharmacodynamics, antiparasitic agents |
description |
Parasiticides have been the most valuable weapons to combat parasites for almost half a century, constituting more than 50 % of veterinary pharmaceuticals and a good part of the products destined for human health. However, in many parts of the world, parasites develop resistance to these drugs, and it is now a major health problem. One way to avoid this inconvenience is the in-depth knowledge of its mechanisms of action, which will allow a more appropriate use. This work is a review of the different physiological aspects of parasite species and an explanation of the different mechanisms of action of antiparasitic agents. Once these drugs are ingested or absorbed by parasites the agents come into contact with the parasites structures, and according to the drug's properties it will define the antiparasitic activity either by altering tegument, carbohydrates, protein and lipid metabolism, or motility of the multicellular parasites. |
format |
Articulo Articulo |
author |
Giordani, C. Marín, Gustavo Horacio Pérez, D. Soraci, Alejandro Luis Errecalde, Jorge Oscar |
author_facet |
Giordani, C. Marín, Gustavo Horacio Pérez, D. Soraci, Alejandro Luis Errecalde, Jorge Oscar |
author_sort |
Giordani, C. |
title |
Mechanism of action of drugs with activity against multicellular parasites |
title_short |
Mechanism of action of drugs with activity against multicellular parasites |
title_full |
Mechanism of action of drugs with activity against multicellular parasites |
title_fullStr |
Mechanism of action of drugs with activity against multicellular parasites |
title_full_unstemmed |
Mechanism of action of drugs with activity against multicellular parasites |
title_sort |
mechanism of action of drugs with activity against multicellular parasites |
publishDate |
2017 |
url |
http://sedici.unlp.edu.ar/handle/10915/98772 https://ri.conicet.gov.ar/11336/58597 https://www.zin.ru/journals/parazitologiya/content/2017/prz_2017_4_3_Giordani.pdf |
work_keys_str_mv |
AT giordanic mechanismofactionofdrugswithactivityagainstmulticellularparasites AT maringustavohoracio mechanismofactionofdrugswithactivityagainstmulticellularparasites AT perezd mechanismofactionofdrugswithactivityagainstmulticellularparasites AT soracialejandroluis mechanismofactionofdrugswithactivityagainstmulticellularparasites AT errecaldejorgeoscar mechanismofactionofdrugswithactivityagainstmulticellularparasites |
bdutipo_str |
Repositorios |
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1764820493192396800 |