Statistical modelling of higher-order correlations in pools of neural activity
Simultaneous recordings from multiple neural units allow us to investigate the activity of very large neural ensembles. To understand how large ensembles of neurons process sensory information, it is necessary to develop suitable statistical models to describe the response variability of the record...
| Autores principales: | , , , |
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| Formato: | Articulo Preprint |
| Lenguaje: | Inglés |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/97220 https://ri.conicet.gov.ar/11336/23406 https://arxiv.org/abs/1211.6348 |
| Aporte de: |
| id |
I19-R120-10915-97220 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Física Neural activity Spike correlations High-order correlations Information-geometry approach |
| spellingShingle |
Física Neural activity Spike correlations High-order correlations Information-geometry approach Montani, Fernando Fabián Phoka, Elena Portesi, Mariela Adelina Schultz, Simon R. Statistical modelling of higher-order correlations in pools of neural activity |
| topic_facet |
Física Neural activity Spike correlations High-order correlations Information-geometry approach |
| description |
Simultaneous recordings from multiple neural units allow us to investigate the activity of very large neural ensembles. To understand how large ensembles of neurons process sensory information, it is necessary to develop suitable statistical models to describe the response variability of the recorded spike trains. Using the information geometry framework, it is possible to estimate higher-order correlations by assigning one interaction parameter to each degree of correlation, leading to a (2^N-1)-dimensional model for a population with N neurons. However, this model suffers greatly from a combinatorial explosion, and the number of parameters to be estimated from the available sample size constitutes the main intractability reason of this approach. To quantify the extent of higher than pairwise spike correlations in pools of multiunit activity, we use an information-geometric approach within the framework of the extended central limit theorem considering all possible contributions from higher-order spike correlations. The identification of a deformation parameter allows us to provide a statistical characterisation of the amount of higher-order correlations in the case of a very large neural ensemble, significantly reducing the number of parameters, avoiding the sampling problem, and inferring the underlying dynamical properties of the network within pools of multiunit neural activity. |
| format |
Articulo Preprint |
| author |
Montani, Fernando Fabián Phoka, Elena Portesi, Mariela Adelina Schultz, Simon R. |
| author_facet |
Montani, Fernando Fabián Phoka, Elena Portesi, Mariela Adelina Schultz, Simon R. |
| author_sort |
Montani, Fernando Fabián |
| title |
Statistical modelling of higher-order correlations in pools of neural activity |
| title_short |
Statistical modelling of higher-order correlations in pools of neural activity |
| title_full |
Statistical modelling of higher-order correlations in pools of neural activity |
| title_fullStr |
Statistical modelling of higher-order correlations in pools of neural activity |
| title_full_unstemmed |
Statistical modelling of higher-order correlations in pools of neural activity |
| title_sort |
statistical modelling of higher-order correlations in pools of neural activity |
| publishDate |
2013 |
| url |
http://sedici.unlp.edu.ar/handle/10915/97220 https://ri.conicet.gov.ar/11336/23406 https://arxiv.org/abs/1211.6348 |
| work_keys_str_mv |
AT montanifernandofabian statisticalmodellingofhigherordercorrelationsinpoolsofneuralactivity AT phokaelena statisticalmodellingofhigherordercorrelationsinpoolsofneuralactivity AT portesimarielaadelina statisticalmodellingofhigherordercorrelationsinpoolsofneuralactivity AT schultzsimonr statisticalmodellingofhigherordercorrelationsinpoolsofneuralactivity |
| bdutipo_str |
Repositorios |
| _version_ |
1764820492466782210 |