Pharmaceuticals and personal care products in the environment: What are the big questions?

Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key...

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Autores principales: Boxall, Alistair B. A., Rudd, Murray A., Brooks, Bryan W., Caldwell, Daniel J., Choi, Kyungho, Hickmann, Silke, Innes, Elizabeth, Ostapyk, Kim, Staveley, Jane P., Verslycke, Tim, Ankley, Gerald T., Beazley, Karen F., Belanger, Scott E., Berninger, Jason P., Carriquiriborde, Pedro, Coors, Anja, DeLeo, Paul C., Dyer, Scott D., Ericson, Jon F., Gagné, François, Giesy, John P., Gouin, Todd, Hallstrom, Lars, Karlsson, Maja V., Joakim Larsson, D.G., Lazorchak, James M., Mastrocco, Frank, McLaughlin, Alison, McMaster, Mark E., Meyerhoff, Roger D., Moore, Roberta, Parrott, Joanne L., Snape, Jason R., Murray-Smith, Richard, Servos, Mark R., Sibley, Paul K., Straub, Jürg Oliver, Szabo, Nora D., Topp, Edward, Tetreault, Gerald R., Trudeau, Vance L., Van Der Kraak, Glen
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/96195
https://ri.conicet.gov.ar/11336/81809
https://ehp.niehs.nih.gov/doi/10.1289/ehp.1104477
Aporte de:
id I19-R120-10915-96195
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
spellingShingle Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
Boxall, Alistair B. A.
Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
Pharmaceuticals and personal care products in the environment: What are the big questions?
topic_facet Biología
Antibiotic resistance
Ecotoxicity
Exposure assessment
Health effects
Personal care products
Pharmaceuticals
Prioritization
Risk assessment
Risk management
description Background: Over the past 10-15 years, a substantial amount of work has been done by the scientific, regulatory, and business communities to elucidate the effects and risks of pharmaceuticals and personal care products (PPCPs) in the environment. Objective: This review was undertaken to identify key outstanding issues regarding the effects of PPCPs on human and ecological health in order to ensure that future resources will be focused on the most important areas. Data sources: To better understand and manage the risks of PPCPs in the environment, we used the "key question" approach to identify the principle issues that need to be addressed. Initially, questions were solicited from academic, government, and business communities around the world. A list of 101 questions was then discussed at an international expert workshop, and a top-20 list was developed. Following the workshop, workshop attendees ranked the 20 questions by importance. Data synthesis: The top 20 priority questions fell into seven categories: a) prioritization of substances for assessment, b) pathways of exposure, c) bioavailability and uptake, d) effects characterization, e) risk and relative risk, f) antibiotic resistance, and g) risk management. Conclusions: A large body of information is now available on PPCPs in the environment. This exercise prioritized the most critical questions to aid in development of future research programs on the topic.
format Articulo
Articulo
author Boxall, Alistair B. A.
Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
author_facet Boxall, Alistair B. A.
Rudd, Murray A.
Brooks, Bryan W.
Caldwell, Daniel J.
Choi, Kyungho
Hickmann, Silke
Innes, Elizabeth
Ostapyk, Kim
Staveley, Jane P.
Verslycke, Tim
Ankley, Gerald T.
Beazley, Karen F.
Belanger, Scott E.
Berninger, Jason P.
Carriquiriborde, Pedro
Coors, Anja
DeLeo, Paul C.
Dyer, Scott D.
Ericson, Jon F.
Gagné, François
Giesy, John P.
Gouin, Todd
Hallstrom, Lars
Karlsson, Maja V.
Joakim Larsson, D.G.
Lazorchak, James M.
Mastrocco, Frank
McLaughlin, Alison
McMaster, Mark E.
Meyerhoff, Roger D.
Moore, Roberta
Parrott, Joanne L.
Snape, Jason R.
Murray-Smith, Richard
Servos, Mark R.
Sibley, Paul K.
Straub, Jürg Oliver
Szabo, Nora D.
Topp, Edward
Tetreault, Gerald R.
Trudeau, Vance L.
Van Der Kraak, Glen
author_sort Boxall, Alistair B. A.
title Pharmaceuticals and personal care products in the environment: What are the big questions?
title_short Pharmaceuticals and personal care products in the environment: What are the big questions?
title_full Pharmaceuticals and personal care products in the environment: What are the big questions?
title_fullStr Pharmaceuticals and personal care products in the environment: What are the big questions?
title_full_unstemmed Pharmaceuticals and personal care products in the environment: What are the big questions?
title_sort pharmaceuticals and personal care products in the environment: what are the big questions?
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/96195
https://ri.conicet.gov.ar/11336/81809
https://ehp.niehs.nih.gov/doi/10.1289/ehp.1104477
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