The Identification of New Histamine Derivatives in the Skin of Leptodactylus

Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthi...

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Detalles Bibliográficos
Autores principales: Erspamer, V., Vitali, T., Roseghini, M., Cei, José Miguel Alfredo María
Formato: Articulo
Lenguaje:Inglés
Publicado: 1964
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/89940
Aporte de:
id I19-R120-10915-89940
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Zoología
Skin
Amphibians
Leptodactylus
spellingShingle Zoología
Skin
Amphibians
Leptodactylus
Erspamer, V.
Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
The Identification of New Histamine Derivatives in the Skin of Leptodactylus
topic_facet Zoología
Skin
Amphibians
Leptodactylus
description Extracts of the skin of some South American amphibians belonging to the genus Leptodactylus contain, in addition to 5-hydroxyindolealkylamines and hydroxyphenylalkylamines, remarkable amounts of imidazolealkylamines. The species most rich in these compounds are Leptodactylus pentadactylus labyrinthicus and Leptodactylus laticeps. The skin of the former species contains not only histamine, N'-methyl- histamine and N', N'-dimethylhistamine but also two imidazo-c-pyridine derivatives hitherto unknown in nature: spinaceamine and 6-methylspinaceamine. The new findings permit a notable enlargement of our knowledge in the field of biogenic imidazolealkylamines and illustrate new possible metabolic pathways for histamine.
format Articulo
Articulo
author Erspamer, V.
Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
author_facet Erspamer, V.
Vitali, T.
Roseghini, M.
Cei, José Miguel Alfredo María
author_sort Erspamer, V.
title The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_short The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_full The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_fullStr The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_full_unstemmed The Identification of New Histamine Derivatives in the Skin of Leptodactylus
title_sort identification of new histamine derivatives in the skin of leptodactylus
publishDate 1964
url http://sedici.unlp.edu.ar/handle/10915/89940
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