Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL

This article supports experimental evidence on the time-dependent effect on gene expression related to inflammation and cholesterol deposition in lipid-loaded cells. The cells employed were human monocytes THP1 line transformed into macrophages by treatment with phorbol esters. Macrophages were trea...

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Autores principales: Toledo, Juan, Esteve, Montserrat, Grasa, Mar, Ledda, Angelo, Garda, Horacio Alberto, Gulfo, José, Díaz Ludovico, Ivo, Ramella, Nahuel Alberto, González, Marina Cecilia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2016
Materias:
Ciencias Médicas
Cell viability
Low density lipoprotein
Macrophages
Peroxidative damage
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/85990
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-85990
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Cell viability
Low density lipoprotein
Macrophages
Peroxidative damage
spellingShingle Ciencias Médicas
Cell viability
Low density lipoprotein
Macrophages
Peroxidative damage
Toledo, Juan
Esteve, Montserrat
Grasa, Mar
Ledda, Angelo
Garda, Horacio Alberto
Gulfo, José
Díaz Ludovico, Ivo
Ramella, Nahuel Alberto
González, Marina Cecilia
Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
topic_facet Ciencias Médicas
Cell viability
Low density lipoprotein
Macrophages
Peroxidative damage
description This article supports experimental evidence on the time-dependent effect on gene expression related to inflammation and cholesterol deposition in lipid-loaded cells. The cells employed were human monocytes THP1 line transformed into macrophages by treatment with phorbol esters. Macrophages were treated at different times with oxidized low density lipoprotein (Ox-LDL) and then gene expression was measured. We also include data about the different types of oxidized lipoprotein obtained (low, media or high oxidation) for differential exposure with Cu ions. These data include characterization to lipid and protein peroxidative damage and also quantification of cell viability by exposure to native and modified LDL. The present article complements data published in "Decreased OxLDL uptake and cholesterol efflux in THP1 cells elicited by cortisol and by cortisone through 11β-hydroxysteroid dehydrogenase type 1" Ledda et al. (in press) [. 1].
format Articulo
Articulo
author Toledo, Juan
Esteve, Montserrat
Grasa, Mar
Ledda, Angelo
Garda, Horacio Alberto
Gulfo, José
Díaz Ludovico, Ivo
Ramella, Nahuel Alberto
González, Marina Cecilia
author_facet Toledo, Juan
Esteve, Montserrat
Grasa, Mar
Ledda, Angelo
Garda, Horacio Alberto
Gulfo, José
Díaz Ludovico, Ivo
Ramella, Nahuel Alberto
González, Marina Cecilia
author_sort Toledo, Juan
title Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
title_short Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
title_full Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
title_fullStr Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
title_full_unstemmed Data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified LDL
title_sort data related to inflammation and cholesterol deposition triggered by macrophages exposition to modified ldl
publishDate 2016
url http://sedici.unlp.edu.ar/handle/10915/85990
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