Development of improved pertussis vaccine

Rates of infection with <i>Bordetella pertussis</i>, the gram-negative bacterium that causes the respiratory disease called whooping cough or pertussis, have not abated and 16 million cases with almost 200,000 deaths are estimated by the WHO to have occurred worldwide in 2008. Despite re...

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Detalles Bibliográficos
Autores principales: Rumbo, Martín, Hozbor, Daniela Flavia
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2014
Materias:
Ciencias Exactas
Bordetella parapertussis
Bordetella pertussis
Pertussis
Vaccines
Whooping cough
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/85088
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-85088
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Bordetella parapertussis
Bordetella pertussis
Pertussis
Vaccines
Whooping cough
spellingShingle Ciencias Exactas
Bordetella parapertussis
Bordetella pertussis
Pertussis
Vaccines
Whooping cough
Rumbo, Martín
Hozbor, Daniela Flavia
Development of improved pertussis vaccine
topic_facet Ciencias Exactas
Bordetella parapertussis
Bordetella pertussis
Pertussis
Vaccines
Whooping cough
description Rates of infection with <i>Bordetella pertussis</i>, the gram-negative bacterium that causes the respiratory disease called whooping cough or pertussis, have not abated and 16 million cases with almost 200,000 deaths are estimated by the WHO to have occurred worldwide in 2008. Despite relatively high vaccination rates, the disease has come back in recent years to afflict people in numbers not seen since the pre-vaccine days. Indeed, pertussis is now recognized as a frequent infection not only in newborn and infants but also in adults. The disease symptoms also can be induced by the non-vaccine-preventable infection with the close species <i>B. parapertussis</i> for which an increasing number of cases have been reported. The epidemiologic situation and current knowledge of the limitations of pertussis vaccine point out the need to design improved vaccines. Several alternative approaches and their challenges are summarized.
format Articulo
Comunicacion
author Rumbo, Martín
Hozbor, Daniela Flavia
author_facet Rumbo, Martín
Hozbor, Daniela Flavia
author_sort Rumbo, Martín
title Development of improved pertussis vaccine
title_short Development of improved pertussis vaccine
title_full Development of improved pertussis vaccine
title_fullStr Development of improved pertussis vaccine
title_full_unstemmed Development of improved pertussis vaccine
title_sort development of improved pertussis vaccine
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/85088
work_keys_str_mv AT rumbomartin developmentofimprovedpertussisvaccine
AT hozbordanielaflavia developmentofimprovedpertussisvaccine
bdutipo_str Repositorios
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