The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced

The establishment of the anterior-posterior segmentation in insects requires the concerted action of a hierarchical gene network. Here, we study the orthologue of <i>Krüppel</i> gap gene in the hemipteran <i>Rhodnius prolixus</i> (<i>Rp</i>-<i>Kr</i>)....

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Detalles Bibliográficos
Autores principales: Lavore, Andrés E., Esponda Behrens, Natalia, Pagola, Lucía Elena, Rivera Pomar, Rolando Víctor
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
Materias:
Ciencias Exactas
Gap gene
Hox regulation
Krüppel
Rhodnius
Segmentation
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/85060
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-85060
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Gap gene
Hox regulation
Krüppel
Rhodnius
Segmentation
spellingShingle Ciencias Exactas
Gap gene
Hox regulation
Krüppel
Rhodnius
Segmentation
Lavore, Andrés E.
Esponda Behrens, Natalia
Pagola, Lucía Elena
Rivera Pomar, Rolando Víctor
The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
topic_facet Ciencias Exactas
Gap gene
Hox regulation
Krüppel
Rhodnius
Segmentation
description The establishment of the anterior-posterior segmentation in insects requires the concerted action of a hierarchical gene network. Here, we study the orthologue of <i>Krüppel</i> gap gene in the hemipteran <i>Rhodnius prolixus</i> (<i>Rp</i>-<i>Kr</i>). We characterized its structure, expression pattern and function. The genomic sequence upstream of the <i>Rp</i>-<i>Kr</i> transcriptional unit shows a putative regulatory region conserved in the orthologue genes from <i>Drosophila melanogaster</i> and <i>Tribolium castaneum</i>. <i>Rp</i>-<i>Kr</i> expression is zygotic and it is expressed in the anterior half of the embryo (the posterior half of the egg) during the blastoderm stage and germ band formation; later, during germ band extension, it is expressed in a central domain, from T2 to A3. The <i>Rp</i>-<i>Kr</i> loss of function phenotypes shows disrupted thoracic and abdominal segmentation. Embryos with weak segmentation phenotypes show homeotic transformations, in which an ectopic tibial comb, typical of T1 leg, appears in T2, which correlates with the ectopic expression of <i>Rp-sex-comb reduced</i> in this leg.
format Articulo
Articulo
author Lavore, Andrés E.
Esponda Behrens, Natalia
Pagola, Lucía Elena
Rivera Pomar, Rolando Víctor
author_facet Lavore, Andrés E.
Esponda Behrens, Natalia
Pagola, Lucía Elena
Rivera Pomar, Rolando Víctor
author_sort Lavore, Andrés E.
title The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
title_short The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
title_full The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
title_fullStr The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
title_full_unstemmed The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
title_sort gap gene krüppel of rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/85060
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