Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina

A total of 120 Burkholderia cepacia complex isolates collected during 2004-2010 from 66 patients in two cystic fibrosis reference centers in Argentina were analyzed. Burkholderia contaminans was the species most frequently recovered (57.6%), followed by Burkholderia cenocepacia (15%), a species dist...

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Detalles Bibliográficos
Autores principales: Martina, Pablo Francisco, Bettiol, Marisa, Vescina, Cecilia, Montanaro, Patricia, Mannino, María Constanza, Prieto, Claudia Inés, Vay, Carlos, Naumann, Dieter, Schmitt, Juergen, Yantorno, Osvaldo Miguel, Lagares, Antonio, Bosch, María Alejandra
Formato: Articulo
Lenguaje:Inglés
Publicado: 2013
Materias:
Biología
Burkholderia
cystic fibrosis
BOXPCR genotyping
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84971
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-84971
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
Burkholderia
cystic fibrosis
BOXPCR genotyping
spellingShingle Biología
Burkholderia
cystic fibrosis
BOXPCR genotyping
Martina, Pablo Francisco
Bettiol, Marisa
Vescina, Cecilia
Montanaro, Patricia
Mannino, María Constanza
Prieto, Claudia Inés
Vay, Carlos
Naumann, Dieter
Schmitt, Juergen
Yantorno, Osvaldo Miguel
Lagares, Antonio
Bosch, María Alejandra
Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
topic_facet Biología
Burkholderia
cystic fibrosis
BOXPCR genotyping
description A total of 120 Burkholderia cepacia complex isolates collected during 2004-2010 from 66 patients in two cystic fibrosis reference centers in Argentina were analyzed. Burkholderia contaminans was the species most frequently recovered (57.6%), followed by Burkholderia cenocepacia (15%), a species distribution not reported so far. The recA-PCR-based techniques applied to the B. contaminans isolates revealed that 85% of the population carried the recA-ST-71 allele. Our results showed the utility of BOXPCR genotyping in analyzing B. contaminans diversity. This approach allowed us to address clonal transmission during an outbreak and the genetic changes occurring in infecting bacteria over the course of chronic infection.
format Articulo
Articulo
author Martina, Pablo Francisco
Bettiol, Marisa
Vescina, Cecilia
Montanaro, Patricia
Mannino, María Constanza
Prieto, Claudia Inés
Vay, Carlos
Naumann, Dieter
Schmitt, Juergen
Yantorno, Osvaldo Miguel
Lagares, Antonio
Bosch, María Alejandra
author_facet Martina, Pablo Francisco
Bettiol, Marisa
Vescina, Cecilia
Montanaro, Patricia
Mannino, María Constanza
Prieto, Claudia Inés
Vay, Carlos
Naumann, Dieter
Schmitt, Juergen
Yantorno, Osvaldo Miguel
Lagares, Antonio
Bosch, María Alejandra
author_sort Martina, Pablo Francisco
title Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
title_short Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
title_full Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
title_fullStr Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
title_full_unstemmed Genetic diversity of Burkholderia contaminans isolates from cystic fibrosis patients in Argentina
title_sort genetic diversity of burkholderia contaminans isolates from cystic fibrosis patients in argentina
publishDate 2013
url http://sedici.unlp.edu.ar/handle/10915/84971
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