Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?

Kirimanjeswara et al. studied the role of B cells and antibodies in immunity to Bordetella by using murine infection models for Bordetella bronchiseptica and the human pathogens B. pertussis and B. parapertussis. They showed that although B cells are required for efficient clearance of all three Bor...

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Detalles Bibliográficos
Autores principales: Rodríguez, María Eugenia, Van der Pol, W. Ludo
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2003
Materias:
Biología
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84785
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-84785
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
spellingShingle Biología
Rodríguez, María Eugenia
Van der Pol, W. Ludo
Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
topic_facet Biología
description Kirimanjeswara et al. studied the role of B cells and antibodies in immunity to Bordetella by using murine infection models for Bordetella bronchiseptica and the human pathogens B. pertussis and B. parapertussis. They showed that although B cells are required for efficient clearance of all three Bordetella species, intraperitoneal injection of murine immune sera results in clearance of B. bronchiseptica, whereas the human pathogens persist. From these data and results of previously published studies which failed to show opsonic activity of human immune sera in vitro, they conclude that Bordetella species that are pathogenic for humans may have acquired the capacity to evade the human humoral immune response. The study by Kirimanjeswara and colleagues is a valuable contribution to the field. However, an alternative explanation for their results should not remain unmentioned.
format Articulo
Comunicacion
author Rodríguez, María Eugenia
Van der Pol, W. Ludo
author_facet Rodríguez, María Eugenia
Van der Pol, W. Ludo
author_sort Rodríguez, María Eugenia
title Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
title_short Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
title_full Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
title_fullStr Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
title_full_unstemmed Letter to the Editor: Humoral Immunity against Bordetella pertussis: Antibodies or B Cells?
title_sort letter to the editor: humoral immunity against bordetella pertussis: antibodies or b cells?
publishDate 2003
url http://sedici.unlp.edu.ar/handle/10915/84785
work_keys_str_mv AT rodriguezmariaeugenia lettertotheeditorhumoralimmunityagainstbordetellapertussisantibodiesorbcells
AT vanderpolwludo lettertotheeditorhumoralimmunityagainstbordetellapertussisantibodiesorbcells
bdutipo_str Repositorios
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