In vitro effects of ivermectin upon trichomonas vaginalis trophozoites

Trichomoniasis is the most common, curable sexually transmitted disease in the world. The first line treatment of trichomoniasis is metronidazole. Recently, the resistance of T. vaginalis to metronidazole and imidazoles has been shown to increase. Ivermectin is a synthetic machrolid drug with activi...

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Autores principales: Vargas Villarreal, Javier, Cortes Gutiérrez, Elva I., Garza González, Jesús N., Rivera Silva, Gerardo, Mata Cárdenas, Benito D., González Salazar, Francisco
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2012
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8444
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_2_3.pdf
Aporte de:
id I19-R120-10915-8444
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Trichomonas vaginalis
Ivermectina
spellingShingle Farmacia
Trichomonas vaginalis
Ivermectina
Vargas Villarreal, Javier
Cortes Gutiérrez, Elva I.
Garza González, Jesús N.
Rivera Silva, Gerardo
Mata Cárdenas, Benito D.
González Salazar, Francisco
In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
topic_facet Farmacia
Trichomonas vaginalis
Ivermectina
description Trichomoniasis is the most common, curable sexually transmitted disease in the world. The first line treatment of trichomoniasis is metronidazole. Recently, the resistance of T. vaginalis to metronidazole and imidazoles has been shown to increase. Ivermectin is a synthetic machrolid drug with activity versus endo and ectoparasitic organisms. In this assay, was tested the effects of ivermectin on T. vaginalis trophozoites. Ivermectin have anti-parasitic activity upon trichomonas trophozoites. However, the IC50 of ivermectin against T. vaginalis was high compared with metronidazole.
format Articulo
Comunicacion
author Vargas Villarreal, Javier
Cortes Gutiérrez, Elva I.
Garza González, Jesús N.
Rivera Silva, Gerardo
Mata Cárdenas, Benito D.
González Salazar, Francisco
author_facet Vargas Villarreal, Javier
Cortes Gutiérrez, Elva I.
Garza González, Jesús N.
Rivera Silva, Gerardo
Mata Cárdenas, Benito D.
González Salazar, Francisco
author_sort Vargas Villarreal, Javier
title In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
title_short In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
title_full In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
title_fullStr In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
title_full_unstemmed In vitro effects of ivermectin upon trichomonas vaginalis trophozoites
title_sort in vitro effects of ivermectin upon trichomonas vaginalis trophozoites
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/8444
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_2_3.pdf
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