Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.

The chemical composition of the essential oils from leaves and stems of Eugenia sulcata Spring ex Mart., obtained by hydrodistillation, was analyzed by GC-MS and quantified by CG-FID. In all, 37 components were identified and sesquiterpenes represented the largest fraction of both oils, in the leave...

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Autores principales: Rocha, Leandro, Silva Filho, Moacélio V., Santos, Marcelo G., Botas, Gisele da S., Cruz, Rodrigo A.S., Fernandes, Caio P., Tietbohl, Luis A. C., Lima, Barbara G.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
aceite esencial
Myrtaceae
Eugenia
Acetilcolinesterasa
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8443
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_2_2.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8443
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
aceite esencial
Myrtaceae
Eugenia
Acetilcolinesterasa
spellingShingle Farmacia
aceite esencial
Myrtaceae
Eugenia
Acetilcolinesterasa
Rocha, Leandro
Silva Filho, Moacélio V.
Santos, Marcelo G.
Botas, Gisele da S.
Cruz, Rodrigo A.S.
Fernandes, Caio P.
Tietbohl, Luis A. C.
Lima, Barbara G.
Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
topic_facet Farmacia
aceite esencial
Myrtaceae
Eugenia
Acetilcolinesterasa
description The chemical composition of the essential oils from leaves and stems of Eugenia sulcata Spring ex Mart., obtained by hydrodistillation, was analyzed by GC-MS and quantified by CG-FID. In all, 37 components were identified and sesquiterpenes represented the largest fraction of both oils, in the leaves (58.2 %) and stems (85.3 %). The major constituent found in the essential oil from leaves and stems of E. sulcata was β-caryophyllene, corresponding to 24.6 % and 18.8 %, respectively. The substances α- cubebene (1.1 %), β-copaene (0.5 %), cis-muurola-3,5-diene (0.6 %), cis-muurola-4(14),5-diene (1.3 %), γ- himachalene (2.0 %), epizonarene (0.8 %), trans-calamenene (4.4 %) and trans-cadina-1,4-diene (3.4 %) were identified for the first time as chemical constituents of essential oil from leaves of E. sulcata. To our knowledge, this was the first phytochemical contribution to the essential oil from stems of E. sulcata. It was also performed the acetylcholinesterase inhibitory bioassay of the essential oil from leaves of E. sulcata, which was considered active and exhibited an IC50 value of 4.66 ± 0.48 μg.mL<sup>-1</sup>.
format Articulo
Comunicacion
author Rocha, Leandro
Silva Filho, Moacélio V.
Santos, Marcelo G.
Botas, Gisele da S.
Cruz, Rodrigo A.S.
Fernandes, Caio P.
Tietbohl, Luis A. C.
Lima, Barbara G.
author_facet Rocha, Leandro
Silva Filho, Moacélio V.
Santos, Marcelo G.
Botas, Gisele da S.
Cruz, Rodrigo A.S.
Fernandes, Caio P.
Tietbohl, Luis A. C.
Lima, Barbara G.
author_sort Rocha, Leandro
title Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
title_short Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
title_full Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
title_fullStr Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
title_full_unstemmed Chemical composition of essential oils and anticholinesterasic activity of Eugenia sulcata Spring ex Mart.
title_sort chemical composition of essential oils and anticholinesterasic activity of eugenia sulcata spring ex mart.
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/8443
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_2_2.pdf
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