Incidence of adverse drug reactions at a university hospital in Southern Brazil
We aimed to evaluate the incidence of adverse drug reactions (ADRs) at a hospital, determine the variation in the incidence of ADRs between genders and among age groups, and determine the pharmacological class most often involved in ADRs. A longitudinal prospective study was conducted over a period...
Guardado en:
| Autores principales: | , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8413 http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_25.pdf |
| Aporte de: |
| Sumario: | We aimed to evaluate the incidence of adverse drug reactions (ADRs) at a hospital, determine the variation in the incidence of ADRs between genders and among age groups, and determine the pharmacological class most often involved in ADRs. A longitudinal prospective study was conducted over a period of 5 months by using an active search in all hospital units. Four hundred forty-six patients were followed during their hospitalization; 103 showed ADRs, resulting in a 23 % overall incidence. Suspected ADRs were identified in 136 patients. From this group of patients, 9 reactions were classified as definite (6.6 %), 77 as probable (56.6 %), and 50 as possible (36.8 %). Female gender, patient age less than 65 years, and hospitalization in the Gynecology and Obstetrics Ward were factors associated with a higher incidence of ADR development. The active search is a suitable instrument for assessing the incidence of ADRs in the hospital. |
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