Incidence of adverse drug reactions at a university hospital in Southern Brazil

We aimed to evaluate the incidence of adverse drug reactions (ADRs) at a hospital, determine the variation in the incidence of ADRs between genders and among age groups, and determine the pharmacological class most often involved in ADRs. A longitudinal prospective study was conducted over a period...

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Autores principales: Gonzalez, Cristina, Tust, Patrícia B.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
farmacovigilancia
Hospitales Escuela
Farmacoepidemiología
Incidencia
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8413
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_25.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8413
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
farmacovigilancia
Hospitales Escuela
Farmacoepidemiología
Incidencia
spellingShingle Farmacia
farmacovigilancia
Hospitales Escuela
Farmacoepidemiología
Incidencia
Gonzalez, Cristina
Tust, Patrícia B.
Incidence of adverse drug reactions at a university hospital in Southern Brazil
topic_facet Farmacia
farmacovigilancia
Hospitales Escuela
Farmacoepidemiología
Incidencia
description We aimed to evaluate the incidence of adverse drug reactions (ADRs) at a hospital, determine the variation in the incidence of ADRs between genders and among age groups, and determine the pharmacological class most often involved in ADRs. A longitudinal prospective study was conducted over a period of 5 months by using an active search in all hospital units. Four hundred forty-six patients were followed during their hospitalization; 103 showed ADRs, resulting in a 23 % overall incidence. Suspected ADRs were identified in 136 patients. From this group of patients, 9 reactions were classified as definite (6.6 %), 77 as probable (56.6 %), and 50 as possible (36.8 %). Female gender, patient age less than 65 years, and hospitalization in the Gynecology and Obstetrics Ward were factors associated with a higher incidence of ADR development. The active search is a suitable instrument for assessing the incidence of ADRs in the hospital.
format Articulo
Articulo
author Gonzalez, Cristina
Tust, Patrícia B.
author_facet Gonzalez, Cristina
Tust, Patrícia B.
author_sort Gonzalez, Cristina
title Incidence of adverse drug reactions at a university hospital in Southern Brazil
title_short Incidence of adverse drug reactions at a university hospital in Southern Brazil
title_full Incidence of adverse drug reactions at a university hospital in Southern Brazil
title_fullStr Incidence of adverse drug reactions at a university hospital in Southern Brazil
title_full_unstemmed Incidence of adverse drug reactions at a university hospital in Southern Brazil
title_sort incidence of adverse drug reactions at a university hospital in southern brazil
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8413
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_25.pdf
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bdutipo_str Repositorios
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