Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A

Nanoemulsions are special emulsions that consist in a very small drop with sizes between 20 to 500 nm. When they are intended for topical application, the main problem of nanoemulsions is their low viscosity, which is reflex of the small drop size. It was proposed the attainment of hydrogel-thickned...

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Detalles Bibliográficos
Autores principales: Santos, Orlando D. H., Mezadri, Hygor, Aguiar, Tatiana A., Oliveira, Juliana S.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8407
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_19.pdf
Aporte de:
id I19-R120-10915-8407
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
green coffee seed oil; hidrogel-thickened nanoemulsion; phase inversion
Emulsiones
Palmitatos
Vitamina A
spellingShingle Farmacia
green coffee seed oil; hidrogel-thickened nanoemulsion; phase inversion
Emulsiones
Palmitatos
Vitamina A
Santos, Orlando D. H.
Mezadri, Hygor
Aguiar, Tatiana A.
Oliveira, Juliana S.
Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
topic_facet Farmacia
green coffee seed oil; hidrogel-thickened nanoemulsion; phase inversion
Emulsiones
Palmitatos
Vitamina A
description Nanoemulsions are special emulsions that consist in a very small drop with sizes between 20 to 500 nm. When they are intended for topical application, the main problem of nanoemulsions is their low viscosity, which is reflex of the small drop size. It was proposed the attainment of hydrogel-thickned nanoemulsions with vitamin A palmitate (retinyl palmitate) with green coffee seed oil by phase inversion. Hydrogel-thickned nanoemulsions with drops size ranging between 77 to 110 nm were obtained, depending on the polymer used, with increased viscosity. Rheological profile of developed hydrogel-thickned nanoemulsions was determined, showing the influence of the kind of polymer used, here all presented pseudo-plastic behaviour, with different viscosity measurement. The improvement of the viscosity of the systems, associated with the small droplet size, can be very interesting for vitamin A delivery under the skin.
format Articulo
Articulo
author Santos, Orlando D. H.
Mezadri, Hygor
Aguiar, Tatiana A.
Oliveira, Juliana S.
author_facet Santos, Orlando D. H.
Mezadri, Hygor
Aguiar, Tatiana A.
Oliveira, Juliana S.
author_sort Santos, Orlando D. H.
title Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
title_short Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
title_full Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
title_fullStr Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
title_full_unstemmed Hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin A
title_sort hydrogel-thickened nanoemulsion with green coffee seed oil for topical delivery of vitamin a
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8407
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_19.pdf
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AT mezadrihygor hydrogelthickenednanoemulsionwithgreencoffeeseedoilfortopicaldeliveryofvitamina
AT aguiartatianaa hydrogelthickenednanoemulsionwithgreencoffeeseedoilfortopicaldeliveryofvitamina
AT oliveirajulianas hydrogelthickenednanoemulsionwithgreencoffeeseedoilfortopicaldeliveryofvitamina
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