Development and sedative effect of a new formulation of midazolam in chocolate bars

The aim of this work was to assess the stability and sedative effect of midazolam in chocolate bars. The stability of 5 g chocolate bars containing 6 mg midazolam hydrochloride was evaluated at room temperature (25 ± 2 °C), at 4 and 40 °C, by HPLC. Drug plasma levels were measured and the sedative e...

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Autores principales: Flores Pérez, Carmen, Juárez Olguín, Hugo, Flores Pérez, Janett, Ramírez Mendiola, Blanca, González Zamora, José F., Alemón Medina, Radamés, Rivera Espinosa, Liliana, Chávez Pacheco, Juan L.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8404
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_16.pdf
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