Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary

A fast and simple HPLC-PDA method for rosmarinic acid quantification in Rosemary leaves powder was validated. The analyses were performed using a C18 column in isocratic conditions and detection at 254 nm. Performing the system suitability tests, the method showed to be capable of providing data of...

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Detalles Bibliográficos
Autores principales: Bara, María Teresa. F., Rezende, Kênnia R., Alves, Suzana F., Oliveira, Ezequiane M. S., Chaul, Luiza T., Conceição, Edmilson C. da, Couto, Renê O., Paula, José R. de
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8400
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_12.pdf
Aporte de:
id I19-R120-10915-8400
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Cromatografía Liquida
Fenoles
Rosmarinus officinalis
spellingShingle Farmacia
Cromatografía Liquida
Fenoles
Rosmarinus officinalis
Bara, María Teresa. F.
Rezende, Kênnia R.
Alves, Suzana F.
Oliveira, Ezequiane M. S.
Chaul, Luiza T.
Conceição, Edmilson C. da
Couto, Renê O.
Paula, José R. de
Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
topic_facet Farmacia
Cromatografía Liquida
Fenoles
Rosmarinus officinalis
description A fast and simple HPLC-PDA method for rosmarinic acid quantification in Rosemary leaves powder was validated. The analyses were performed using a C18 column in isocratic conditions and detection at 254 nm. Performing the system suitability tests, the method showed to be capable of providing data of acceptable quality. Results showed that the method was selective, linear for concentration ranges between 2.5-50 μg.mL–1 , sensitive, precise, accurate and robust. The main advantages of the method were the simplicity and promptness of sample analysis, as well as equipment convenience. These results allowed us to conclude that it can be successfully applied on the routinely quality control of Rosemary phytopharmaceuticals inputs.
format Articulo
Articulo
author Bara, María Teresa. F.
Rezende, Kênnia R.
Alves, Suzana F.
Oliveira, Ezequiane M. S.
Chaul, Luiza T.
Conceição, Edmilson C. da
Couto, Renê O.
Paula, José R. de
author_facet Bara, María Teresa. F.
Rezende, Kênnia R.
Alves, Suzana F.
Oliveira, Ezequiane M. S.
Chaul, Luiza T.
Conceição, Edmilson C. da
Couto, Renê O.
Paula, José R. de
author_sort Bara, María Teresa. F.
title Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
title_short Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
title_full Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
title_fullStr Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
title_full_unstemmed Validated HPLC-PDA method for rosmarinic acid quantification in Rosemary
title_sort validated hplc-pda method for rosmarinic acid quantification in rosemary
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8400
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_12.pdf
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