Triptolide modulates adriamycin sensitivity via regulating Mir-21 and Bcl-2 expression in K562/A02 cell line

Drug resistance is a major obstacle for successful treatment of leukemia. Increasing evidence suggests that microRNA-21 (miR-21) is over-expressed in K562/A02 cell line, promoting drug resistance. The aim of our present study is to investigate the reversal effects of triptolide on drug resistance in...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolan, Long, Lulu, Chen, Qiaoyun, Shen, Huiling, Xu, Wenlin, Hui, Lulu, Li, Hao
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Leucemia
Resistencia a Medicamentos
MicroARNs
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8395
http://www.latamjpharm.org/resumenes/30/10/LAJOP_30_10_1_7.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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