Determination of sulpiride in rabbit plasma by LC-ESI-MS and its application to a pharmacokinetic study

A sensitive and selective liquid chromatography-mass spectrometry (LC-MS) method for determination of sulpiride in rabbit plasma was developed and validated. The analyte and internal standard (IS) were extracted from plasma by liquid-liquid extraction using ethyl acetate, and chromatography involved...

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Autores principales: Lin, Guanyang, Wu, Haiya, Wang, Zhibin, Zhang, Haiyang, Chien, Lianguo, Wang, Xianqin, Hu Lufeng, Ma, Jianshe
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8373
http://www.latamjpharm.org/resumenes/30/9/LAJOP_30_9_1_17.pdf
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