Antidiabetic principle from Eclipta prostrata

The methanol extract of the whole plant of Eclipta prostrata and one of its isolated compounds, eclalbasaponin II were administered to alloxan-induced diabetic rats for 28 and 7 consecutive days, respectively. During the study, a potent antidiabetic activity was observed. Blood sugar was significant...

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Detalles Bibliográficos
Autores principales:	Rahman, Mohammad S., Rahman, Mohammed Z., Begum, Bilkis, Chowdhury, Rasheduzzaman, Islam, Sk. Nazrul, Rashid, Mohammad A.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia Extractos Vegetales diabetes antidiabetic; Eclipta prostrata; saponin; elalbasaponin Plantas Medicinales
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8355 http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_7.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8355
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia Extractos Vegetales diabetes antidiabetic; Eclipta prostrata; saponin; elalbasaponin Plantas Medicinales
spellingShingle	Farmacia Extractos Vegetales diabetes antidiabetic; Eclipta prostrata; saponin; elalbasaponin Plantas Medicinales Rahman, Mohammad S. Rahman, Mohammed Z. Begum, Bilkis Chowdhury, Rasheduzzaman Islam, Sk. Nazrul Rashid, Mohammad A. Antidiabetic principle from Eclipta prostrata
topic_facet	Farmacia Extractos Vegetales diabetes antidiabetic; Eclipta prostrata; saponin; elalbasaponin Plantas Medicinales
description	The methanol extract of the whole plant of Eclipta prostrata and one of its isolated compounds, eclalbasaponin II were administered to alloxan-induced diabetic rats for 28 and 7 consecutive days, respectively. During the study, a potent antidiabetic activity was observed. Blood sugar was significantly (p < 0.001) reduced by E. prostrata extract (300 mg/kg) and eclalbasaponin II (10 mg/kg), as compared to untreated diabetic rats. Analyses of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) showed no significant (p < 0.001) hepatotoxicity by E. prostrata extractive in alloxan-induced diabetic rats when compared to the diabetic control rats.
format	Articulo Comunicacion
author	Rahman, Mohammad S. Rahman, Mohammed Z. Begum, Bilkis Chowdhury, Rasheduzzaman Islam, Sk. Nazrul Rashid, Mohammad A.
author_facet	Rahman, Mohammad S. Rahman, Mohammed Z. Begum, Bilkis Chowdhury, Rasheduzzaman Islam, Sk. Nazrul Rashid, Mohammad A.
author_sort	Rahman, Mohammad S.
title	Antidiabetic principle from Eclipta prostrata
title_short	Antidiabetic principle from Eclipta prostrata
title_full	Antidiabetic principle from Eclipta prostrata
title_fullStr	Antidiabetic principle from Eclipta prostrata
title_full_unstemmed	Antidiabetic principle from Eclipta prostrata
title_sort	antidiabetic principle from eclipta prostrata
publishDate	2011
url	http://sedici.unlp.edu.ar/handle/10915/8355 http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_2_7.pdf
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bdutipo_str	Repositorios
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Antidiabetic principle from Eclipta prostrata

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