Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)

Haematophagous insects incorporate a large amount of blood with each meal, producing a big quantity of urine in a few hours to eliminate the excess water and Na+. Malpighian tubules (MTs) have traditionally been seen as a system that responds to neuroendocrine stimulus. In a related paper, we demons...

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Detalles Bibliográficos
Autores principales: Santini, María Soledad, Ronderos, Jorge Rafael
Formato: Articulo
Lenguaje:Inglés
Publicado: 2007
Materias:
Ciencias Naturales
Allatotropin
Diuresis
Hindgut
Malpighian tubules
Neuropeptide
Triatoma infestans
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83466
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-83466
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Naturales
Allatotropin
Diuresis
Hindgut
Malpighian tubules
Neuropeptide
Triatoma infestans
spellingShingle Ciencias Naturales
Allatotropin
Diuresis
Hindgut
Malpighian tubules
Neuropeptide
Triatoma infestans
Santini, María Soledad
Ronderos, Jorge Rafael
Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
topic_facet Ciencias Naturales
Allatotropin
Diuresis
Hindgut
Malpighian tubules
Neuropeptide
Triatoma infestans
description Haematophagous insects incorporate a large amount of blood with each meal, producing a big quantity of urine in a few hours to eliminate the excess water and Na+. Malpighian tubules (MTs) have traditionally been seen as a system that responds to neuroendocrine stimulus. In a related paper, we demonstrated that MTs of Triatoma infestans produce an autonomous endocrine secretion of an allatotropin-like (AT-like) peptide. In the present study, we report a myostimulatory activity of AT at the level of the hindgut (HG), associated with endocrine mechanisms regulating post-prandial diuresis. Allatotropin induced an increase in frequency and intensity of peristaltic contractions at the level of the HG. The release of the HG content in MTs-HG in vitro preparations undergoing an osmotic shock occurred at different times, depending on the number of MTs present, and there was no release in treatments without MTs. The application of an AT-antiserum to MTs-HG preparations undergoing osmotic shock produced a delay or a long-term blockade of diuresis, depending on the antiserum dilution applied. Similar results were obtained when AT-antiserum was applied in vivo prior to blood intake, decreasing the volume of urine eliminated during the first 2 h. Our results allow us to assign a specific endocrine function to the AT-like peptide released by MTs that is linked to the elimination of urine after blood meals.
format Articulo
Articulo
author Santini, María Soledad
Ronderos, Jorge Rafael
author_facet Santini, María Soledad
Ronderos, Jorge Rafael
author_sort Santini, María Soledad
title Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
title_short Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
title_full Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
title_fullStr Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
title_full_unstemmed Allatotropin-like peptide released by Malpighian tubules induces hindgut activity associated with diuresis in the Chagas disease vector Triatoma infestans (Klug)
title_sort allatotropin-like peptide released by malpighian tubules induces hindgut activity associated with diuresis in the chagas disease vector triatoma infestans (klug)
publishDate 2007
url http://sedici.unlp.edu.ar/handle/10915/83466
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AT ronderosjorgerafael allatotropinlikepeptidereleasedbymalpighiantubulesinduceshindgutactivityassociatedwithdiuresisinthechagasdiseasevectortriatomainfestansklug
bdutipo_str Repositorios
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