SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth

SPARC (secreted protein acidic and rich in cysteine) is a matricellular protein whose overexpression in malignant or tumor-stromal cells is often associated with increased aggressiveness and bad prognosis in a wide range of human cancer types, particularly melanoma. We established the impact that ch...

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Detalles Bibliográficos
Autores principales: Prada, Federico, Benedetti, Lorena G., Bravo, Alicia I., Alvarez, Mariano J., Carbone, Cecilia, Podhajcer, Osvaldo L.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2007
Materias:
Ciencias Médicas
Ciencias Veterinarias
SPARC
human cancer
Melanoma
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83339
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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