Amphotericin B plasma monitoring for one burn child using high-performance liquid chromatography

A bioanalytical micromethod was described for the quantification of amphotericin B in plasma by HPLC. The method showed high absolute recovery, good linearity (0.1-10.0 μg/mL, r2 = 0.999), sensitivity (limits of quantification: 0.1 μg/mL), and acceptable stability. Inter/intraday precisions were 6.8...

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Detalles Bibliográficos
Autores principales: Sanches Giraud, Cristina, Gomez, David S., Campos, Edvaldo V., Azevedo, Rodrigo P. de, Despinoy, Alessandra, Perez, Grazziela S., Ferreira, Marcus C., Santos, Silvia R. C. J.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Macrólidos
amphotericin B; burn child; drug plasma monitoring; HPLC-UV; pharmacokinetics
Cromatografía
Plasma
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8325
http://www.latamjpharm.org/resumenes/30/8/LAJOP_30_8_1_2.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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