Small cell sweat gland carcinoma of childhood

Small cell sweat gland carcinoma appears to represent a very unusual histological type of sweat gland anlage tumour presenting in children. The differential diagnosis from other small blue cell tumours involving the skin is often difficult. The present report confirms the original observation descri...

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Autores principales: Drut, Ricardo, Giménez, O. P., Oliva, J.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2005
Materias:
Ciencias Médicas
cutaneous tumours
children
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83115
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-83115
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
cutaneous tumours
children
spellingShingle Ciencias Médicas
cutaneous tumours
children
Drut, Ricardo
Giménez, O. P.
Oliva, J.
Small cell sweat gland carcinoma of childhood
topic_facet Ciencias Médicas
cutaneous tumours
children
description Small cell sweat gland carcinoma appears to represent a very unusual histological type of sweat gland anlage tumour presenting in children. The differential diagnosis from other small blue cell tumours involving the skin is often difficult. The present report confirms the original observation describing two patients of 2 and 5 years of age harbouring cutaneous tumours. The histology of these lesions showed a monomorphic proliferation of small cells with a high mitotic rate and areas of necrosis. Immunohistochemically, the cells were negative for desmin, cytokeratin 7, cytokeratin 20, Cam 5.2, CD99, chromogranin, CD56, synaptophysin, and S-100, and focally positive for the pancytokeratin marker AE1/AE3, carcinoembryonic antigen (one case), and neurone specific enolase (one case). The prognosis of this type of tumour seems to be good. As more cases are added, the clinical pathological spectrum of the lesion will become better defined.
format Articulo
Articulo
author Drut, Ricardo
Giménez, O. P.
Oliva, J.
author_facet Drut, Ricardo
Giménez, O. P.
Oliva, J.
author_sort Drut, Ricardo
title Small cell sweat gland carcinoma of childhood
title_short Small cell sweat gland carcinoma of childhood
title_full Small cell sweat gland carcinoma of childhood
title_fullStr Small cell sweat gland carcinoma of childhood
title_full_unstemmed Small cell sweat gland carcinoma of childhood
title_sort small cell sweat gland carcinoma of childhood
publishDate 2005
url http://sedici.unlp.edu.ar/handle/10915/83115
work_keys_str_mv AT drutricardo smallcellsweatglandcarcinomaofchildhood
AT gimenezop smallcellsweatglandcarcinomaofchildhood
AT olivaj smallcellsweatglandcarcinomaofchildhood
bdutipo_str Repositorios
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