Effect of total flavones of buckwheat flowers and leaves on protein tyrosine phosphatase 1B expression in type 2 diabetic rats

The total flavone content was obtained from flowers and leaf of buckwheat (Fagopyrum esculentum Moench) by heating reflux method. The effects of the total flavone extract on the protein tyrosine phosphatase 1B (PTP1B) expression in type 2 diabetic rats were evaluated by immunofluorescence, western b...

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Detalles Bibliográficos
Autores principales: Gou, Xiang- Bo, Han, Shu-Ying, Xu, Jing-Man, Yu, Hong, Chu, Jin-Xiu, Wang, Zhi- Lu, Bai, Jing, Cao, Fu-Yuan, Han, Ting
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8309
http://www.latamjpharm.org/resumenes/30/7/LAJOP_30_7_1_20.pdf
Aporte de:SEDICI (UNLP) de Universidad Nacional de La Plata Ver origen
Descripción
Sumario:The total flavone content was obtained from flowers and leaf of buckwheat (Fagopyrum esculentum Moench) by heating reflux method. The effects of the total flavone extract on the protein tyrosine phosphatase 1B (PTP1B) expression in type 2 diabetic rats were evaluated by immunofluorescence, western blotting and real-time quantitative PCR. The results suggested that the total flavone fraction from buckwheat flowers and leaves can significantly decrease the PTP1B expression in liver.