Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
In this work, we report the use of bulk and silica-supported Wells-Dawson acid (H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones and chromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reaction experiments were performed using tolue...
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Autores principales: | , , , , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
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2008
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/83026 |
Aporte de: |
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I19-R120-10915-83026 |
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record_format |
dspace |
institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Química Acid catalysis Chromones Flavones H2P2W18O62.24H2O Silica gel-supported catalyst |
spellingShingle |
Química Acid catalysis Chromones Flavones H2P2W18O62.24H2O Silica gel-supported catalyst Bennardi, Daniel Oscar Romanelli, Gustavo Pablo Jios, Jorge L. Autino, Juan Carlos Baronetti, Graciela T. Thomas, Horacio Jorge Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
topic_facet |
Química Acid catalysis Chromones Flavones H2P2W18O62.24H2O Silica gel-supported catalyst |
description |
In this work, we report the use of bulk and silica-supported Wells-Dawson acid (H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones and chromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reaction experiments were performed using toluene as solvent at reflux and in the absence of solvent, at 110°C. Under these conditions eleven examples were obtained with very good yields (82-91%) and high selectivity. The catalysts were easily recycled and reused without loss of their catalytic activity. The presented synthetic method is a simple, clean and environmentally friendly alternative for synthesizing substituted flavones and chromones. |
format |
Articulo Articulo |
author |
Bennardi, Daniel Oscar Romanelli, Gustavo Pablo Jios, Jorge L. Autino, Juan Carlos Baronetti, Graciela T. Thomas, Horacio Jorge |
author_facet |
Bennardi, Daniel Oscar Romanelli, Gustavo Pablo Jios, Jorge L. Autino, Juan Carlos Baronetti, Graciela T. Thomas, Horacio Jorge |
author_sort |
Bennardi, Daniel Oscar |
title |
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
title_short |
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
title_full |
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
title_fullStr |
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
title_full_unstemmed |
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst |
title_sort |
synthesis of substituted flavones and chromones using a wells-dawson heteropolyacid as catalyst |
publishDate |
2008 |
url |
http://sedici.unlp.edu.ar/handle/10915/83026 |
work_keys_str_mv |
AT bennardidanieloscar synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst AT romanelligustavopablo synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst AT jiosjorgel synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst AT autinojuancarlos synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst AT baronettigracielat synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst AT thomashoraciojorge synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst |
bdutipo_str |
Repositorios |
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1764820488208515078 |