Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst

In this work, we report the use of bulk and silica-supported Wells-Dawson acid (H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones and chromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reaction experiments were performed using tolue...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Bennardi, Daniel Oscar, Romanelli, Gustavo Pablo, Jios, Jorge Luis, Autino, Juan Carlos, Baronetti, Graciela Teresita, Thomas, Horacio Jorge
Formato: Articulo
Lenguaje:Inglés
Publicado: 2008
Materias:
Química
Acid catalysis
Chromones
Flavones
H2P2W18O62.24H2O
Silica gel-supported catalyst
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83026
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-83026
record_format dspace
spelling I19-R120-10915-830262023-08-15T18:39:49Z http://sedici.unlp.edu.ar/handle/10915/83026 Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst Bennardi, Daniel Oscar Romanelli, Gustavo Pablo Jios, Jorge Luis Autino, Juan Carlos Baronetti, Graciela Teresita Thomas, Horacio Jorge 2008 2019-10-10T13:55:44Z en Química Acid catalysis Chromones Flavones H2P2W18O62.24H2O Silica gel-supported catalyst In this work, we report the use of bulk and silica-supported Wells-Dawson acid (H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones and chromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reaction experiments were performed using toluene as solvent at reflux and in the absence of solvent, at 110°C. Under these conditions eleven examples were obtained with very good yields (82-91%) and high selectivity. The catalysts were easily recycled and reused without loss of their catalytic activity. The presented synthetic method is a simple, clean and environmentally friendly alternative for synthesizing substituted flavones and chromones. Centro de Investigación y Desarrollo en Ciencias Aplicadas Facultad de Ciencias Agrarias y Forestales Laboratorio de Servicios a la Industria y al Sistema Científico Articulo Articulo http://creativecommons.org/licenses/by-nc/3.0/ Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0) application/pdf 123-130
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Acid catalysis
Chromones
Flavones
H2P2W18O62.24H2O
Silica gel-supported catalyst
spellingShingle Química
Acid catalysis
Chromones
Flavones
H2P2W18O62.24H2O
Silica gel-supported catalyst
Bennardi, Daniel Oscar
Romanelli, Gustavo Pablo
Jios, Jorge Luis
Autino, Juan Carlos
Baronetti, Graciela Teresita
Thomas, Horacio Jorge
Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
topic_facet Química
Acid catalysis
Chromones
Flavones
H2P2W18O62.24H2O
Silica gel-supported catalyst
description In this work, we report the use of bulk and silica-supported Wells-Dawson acid (H2P2W18O62.24H2O) as reusable, heterogeneous catalysts to obtain substituted flavones and chromones for the cyclization of 1-(2-hydroxyphenyl)-3-aryl-1,3-propanediones. The reaction experiments were performed using toluene as solvent at reflux and in the absence of solvent, at 110°C. Under these conditions eleven examples were obtained with very good yields (82-91%) and high selectivity. The catalysts were easily recycled and reused without loss of their catalytic activity. The presented synthetic method is a simple, clean and environmentally friendly alternative for synthesizing substituted flavones and chromones.
format Articulo
Articulo
author Bennardi, Daniel Oscar
Romanelli, Gustavo Pablo
Jios, Jorge Luis
Autino, Juan Carlos
Baronetti, Graciela Teresita
Thomas, Horacio Jorge
author_facet Bennardi, Daniel Oscar
Romanelli, Gustavo Pablo
Jios, Jorge Luis
Autino, Juan Carlos
Baronetti, Graciela Teresita
Thomas, Horacio Jorge
author_sort Bennardi, Daniel Oscar
title Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
title_short Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
title_full Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
title_fullStr Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
title_full_unstemmed Synthesis of substituted flavones and chromones using a Wells-Dawson heteropolyacid as catalyst
title_sort synthesis of substituted flavones and chromones using a wells-dawson heteropolyacid as catalyst
publishDate 2008
url http://sedici.unlp.edu.ar/handle/10915/83026
work_keys_str_mv AT bennardidanieloscar synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
AT romanelligustavopablo synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
AT jiosjorgeluis synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
AT autinojuancarlos synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
AT baronettigracielateresita synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
AT thomashoraciojorge synthesisofsubstitutedflavonesandchromonesusingawellsdawsonheteropolyacidascatalyst
_version_ 1807220443034157056

Ejemplares similares