Spectrophotometric determination of paracetamol in pharmaceuticals using microwave-assisted hydrolysis and a micellar medium

A new spectrophotometric method employing a micellar medium is proposed for the determination of paracetamol in pharmaceuticals. The method is based on the acid hydrolysis of paracetamol to p-aminophenol (PAP), which under acidic conditions reacts with p-dimethylaminocinnamaldehyde (pDAC), producing...

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Detalles Bibliográficos
Autores principales: Sequinel, Rodrigo, Rufino, José L., Pezza, Helena, Pezza, Leonardo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
microwave; paracetamol; p-dimethylaminocinnamaldehyde; spectrophotometry; surfactant
Acetaminofén
Técnicas de Química Analítica
Hidrólisis
Aminofenoles
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8302
http://www.latamjpharm.org/resumenes/30/7/LAJOP_30_7_1_12.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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