Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue

A series of 7-chloro-3-(2-substituted phenyl-4-oxo-thiazolidin-3-yl)-2-[2-(2,6-dichlorophenyl) amino]benzyl-quinazolin-4(3H)-ones (5a-j) have been synthesized and characterized by elemental analyses as well as IR and NMR spectra. The Schiff bases 4a-j and 4-thiazolidinones 5a-j have been sceened for...

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Detalles Bibliográficos
Autores principales:	Patel, Jaymin C., Patel, Virendra N., Patel, Navin B.
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia antimicrobial activity; diclofenac; quinazolin-4(3H)-one; 4-thiazolidinone Quinazolinas Fenilacetatos Productos con Acción Antimicrobiana Técnicas de Química Analítica
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8294 http://www.latamjpharm.org/resumenes/30/7/LAJOP_30_7_1_4.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia antimicrobial activity; diclofenac; quinazolin-4(3H)-one; 4-thiazolidinone Quinazolinas Fenilacetatos Productos con Acción Antimicrobiana Técnicas de Química Analítica
spellingShingle	Farmacia antimicrobial activity; diclofenac; quinazolin-4(3H)-one; 4-thiazolidinone Quinazolinas Fenilacetatos Productos con Acción Antimicrobiana Técnicas de Química Analítica Patel, Jaymin C. Patel, Virendra N. Patel, Navin B. Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
topic_facet	Farmacia antimicrobial activity; diclofenac; quinazolin-4(3H)-one; 4-thiazolidinone Quinazolinas Fenilacetatos Productos con Acción Antimicrobiana Técnicas de Química Analítica
description	A series of 7-chloro-3-(2-substituted phenyl-4-oxo-thiazolidin-3-yl)-2-[2-(2,6-dichlorophenyl) amino]benzyl-quinazolin-4(3H)-ones (5a-j) have been synthesized and characterized by elemental analyses as well as IR and NMR spectra. The Schiff bases 4a-j and 4-thiazolidinones 5a-j have been sceened for in vitro antimicrobial activity by cup-plate method. Compounds 4f, 4g, 4h, 5f, 5g and 5h possessed very good antibacterial as well as antifungal activity.
format	Articulo Articulo
author	Patel, Jaymin C. Patel, Virendra N. Patel, Navin B.
author_facet	Patel, Jaymin C. Patel, Virendra N. Patel, Navin B.
author_sort	Patel, Jaymin C.
title	Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
title_short	Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
title_full	Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
title_fullStr	Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
title_full_unstemmed	Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue
title_sort	design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3h)-ones of diclofenac analogue
publishDate	2011
url	http://sedici.unlp.edu.ar/handle/10915/8294 http://www.latamjpharm.org/resumenes/30/7/LAJOP_30_7_1_4.pdf
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Design, synthesis and antimicrobial activity of 4-thiazolidinonyl-quinazolin-4(3H)-ones of diclofenac analogue

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