Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC

Semen Persicae was a traditional Chinese medicine for the treatment of diseases such as inflammation and hyperlipemia. Amygdalin was one of the main active ingredients of this traditional Chinese medicine. In this paper, pharmacokinetic study was conducted to obtain pharmacokinetic parameters of amy...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhang, Zhidan, Gao, Wenyuan, Ma, Chaoyi, Liu, Changxiao
Formato: Articulo Comunicacion
Lenguaje:Español
Publicado: 2011
Materias:
Farmacia
Cromatografia líquida de alta eficiencia
semen persicae; amygdalin; pharmacokinetics; one-compartment model
Medicina Tradicional
Glucósidos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8285
http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_2_4.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8285
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Español
topic Farmacia
Cromatografia líquida de alta eficiencia
semen persicae; amygdalin; pharmacokinetics; one-compartment model
Medicina Tradicional
Glucósidos
spellingShingle Farmacia
Cromatografia líquida de alta eficiencia
semen persicae; amygdalin; pharmacokinetics; one-compartment model
Medicina Tradicional
Glucósidos
Zhang, Zhidan
Gao, Wenyuan
Ma, Chaoyi
Liu, Changxiao
Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
topic_facet Farmacia
Cromatografia líquida de alta eficiencia
semen persicae; amygdalin; pharmacokinetics; one-compartment model
Medicina Tradicional
Glucósidos
description Semen Persicae was a traditional Chinese medicine for the treatment of diseases such as inflammation and hyperlipemia. Amygdalin was one of the main active ingredients of this traditional Chinese medicine. In this paper, pharmacokinetic study was conducted to obtain pharmacokinetic parameters of amygadalin after oral administration of Semen Persicae extraction in rat plasma. HPLC-UV was used to determine the concentration of amygdalin in rat plasma at different time points after administration. The main pharmacokinetic parameters of amygdalin in rat were obtained based on the analysis of the plasma sample. The pharmacokinetics of amygdalin was fitted with a one-compartment model and it eliminated relative slowly in rats.
format Articulo
Comunicacion
author Zhang, Zhidan
Gao, Wenyuan
Ma, Chaoyi
Liu, Changxiao
author_facet Zhang, Zhidan
Gao, Wenyuan
Ma, Chaoyi
Liu, Changxiao
author_sort Zhang, Zhidan
title Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
title_short Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
title_full Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
title_fullStr Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
title_full_unstemmed Study on pharmacokinetics of Amygdalin after oral administration of semen persicae extraction in rat plasma by HPLC
title_sort study on pharmacokinetics of amygdalin after oral administration of semen persicae extraction in rat plasma by hplc
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8285
http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_2_4.pdf
work_keys_str_mv AT zhangzhidan studyonpharmacokineticsofamygdalinafteroraladministrationofsemenpersicaeextractioninratplasmabyhplc
AT gaowenyuan studyonpharmacokineticsofamygdalinafteroraladministrationofsemenpersicaeextractioninratplasmabyhplc
AT machaoyi studyonpharmacokineticsofamygdalinafteroraladministrationofsemenpersicaeextractioninratplasmabyhplc
AT liuchangxiao studyonpharmacokineticsofamygdalinafteroraladministrationofsemenpersicaeextractioninratplasmabyhplc
bdutipo_str Repositorios
_version_ 1764820488688762880

Ejemplares similares