Physiology and technology hand in hand for clinical imaging of the microcirculation

Given the growing interest in the study of microcirculation, we believe that an editorial comment about our article should be welcome. Unfortunately, we feel that the editorialists failed to understand our findings. Drs. Takala and Jakob raise some specific issues. First, they emphasize the high sus...

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Autor principal: Dubin, Arnaldo
Formato: Articulo Contribucion a revista
Lenguaje:Inglés
Publicado: 2009
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/82774
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id I19-R120-10915-82774
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Medicina
Circulación Sanguínea
spellingShingle Ciencias Médicas
Medicina
Circulación Sanguínea
Dubin, Arnaldo
Physiology and technology hand in hand for clinical imaging of the microcirculation
topic_facet Ciencias Médicas
Medicina
Circulación Sanguínea
description Given the growing interest in the study of microcirculation, we believe that an editorial comment about our article should be welcome. Unfortunately, we feel that the editorialists failed to understand our findings. Drs. Takala and Jakob raise some specific issues. First, they emphasize the high susceptibility ofthe model to hemorrhage, already addressed in the manuscript. Unfortunately, they fail to realize that reductions of 24% in cardiac output (CO) only marginally increased lactate (1.6 ± 0.3 to 2.4 ± 0.6 mmol/l) and had no effects on systemic and intestinal oxygen consumptions, blood pressure or base excess, while provoking clear microcirculatory changes. These, however, could be tracked non-invasively in the sublingual mucosa, rendering it a potential area for the clinical monitoring of hypoperfusion.
format Articulo
Contribucion a revista
author Dubin, Arnaldo
author_facet Dubin, Arnaldo
author_sort Dubin, Arnaldo
title Physiology and technology hand in hand for clinical imaging of the microcirculation
title_short Physiology and technology hand in hand for clinical imaging of the microcirculation
title_full Physiology and technology hand in hand for clinical imaging of the microcirculation
title_fullStr Physiology and technology hand in hand for clinical imaging of the microcirculation
title_full_unstemmed Physiology and technology hand in hand for clinical imaging of the microcirculation
title_sort physiology and technology hand in hand for clinical imaging of the microcirculation
publishDate 2009
url http://sedici.unlp.edu.ar/handle/10915/82774
work_keys_str_mv AT dubinarnaldo physiologyandtechnologyhandinhandforclinicalimagingofthemicrocirculation
bdutipo_str Repositorios
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