Design, development and in vitro evaluation of swelling gastro retentive drug delivery system for type 2 diabetic patients

The aim of the present study was to develop sustained release swelling tablets containing metformin HCl and confine them into the stomach for enhancement of bioavailability. The different batches were manufactured by wet granulation method with HPMC K200M and HPMC K100M in combination using Minipres...

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Detalles Bibliográficos
Autores principales:	Ige, Pradum P., Gattani, Surendra G.
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia gastric retention; hydroxy propyl methyl cellulose K200M; metformin HCl; swelling matrix tablets; type 2 diabetes mellitus Enfermedades del Sistema Endocrino Sistemas de Liberación de Medicamentos
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8270 http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_1_12.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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