Formulation and evaluation of biphasic release tablet containing diclofenac beads

The purpose of the present research work was to produce a biphasic delivery system for Diclofenac sodium. A dual component tablet made up of a sustained release beads and immediate release tablet coat was prepared by direct compression using super disintegrating agent. Both the beads and coat contai...

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Detalles Bibliográficos
Autores principales:	Sethi, Sunny S., Puri, Dinesh, Bhatele, Vivek, Gonjari, Indrajeet D., Usmane, Avinash
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia alginate; beads; biphasic delivery system; chitosan Sistemas de Liberación de Medicamentos Diclofenaco
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8261 http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_1_3.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8261
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia alginate; beads; biphasic delivery system; chitosan Sistemas de Liberación de Medicamentos Diclofenaco
spellingShingle	Farmacia alginate; beads; biphasic delivery system; chitosan Sistemas de Liberación de Medicamentos Diclofenaco Sethi, Sunny S. Puri, Dinesh Bhatele, Vivek Gonjari, Indrajeet D. Usmane, Avinash Formulation and evaluation of biphasic release tablet containing diclofenac beads
topic_facet	Farmacia alginate; beads; biphasic delivery system; chitosan Sistemas de Liberación de Medicamentos Diclofenaco
description	The purpose of the present research work was to produce a biphasic delivery system for Diclofenac sodium. A dual component tablet made up of a sustained release beads and immediate release tablet coat was prepared by direct compression using super disintegrating agent. Both the beads and coat contained a model drug (diclofenac sodium). The sustained release effect was achieved with polymers chitosan and sodium alginate. The in vitro release profile from these tablets showed the desired biphasic behavior, the diclofenac contained in the fast releasing component was dissolved within 15 min, whereas the drug in the beads was released upto 8 h.
format	Articulo Articulo
author	Sethi, Sunny S. Puri, Dinesh Bhatele, Vivek Gonjari, Indrajeet D. Usmane, Avinash
author_facet	Sethi, Sunny S. Puri, Dinesh Bhatele, Vivek Gonjari, Indrajeet D. Usmane, Avinash
author_sort	Sethi, Sunny S.
title	Formulation and evaluation of biphasic release tablet containing diclofenac beads
title_short	Formulation and evaluation of biphasic release tablet containing diclofenac beads
title_full	Formulation and evaluation of biphasic release tablet containing diclofenac beads
title_fullStr	Formulation and evaluation of biphasic release tablet containing diclofenac beads
title_full_unstemmed	Formulation and evaluation of biphasic release tablet containing diclofenac beads
title_sort	formulation and evaluation of biphasic release tablet containing diclofenac beads
publishDate	2011
url	http://sedici.unlp.edu.ar/handle/10915/8261 http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_1_3.pdf
work_keys_str_mv	AT sethisunnys formulationandevaluationofbiphasicreleasetabletcontainingdiclofenacbeads AT puridinesh formulationandevaluationofbiphasicreleasetabletcontainingdiclofenacbeads AT bhatelevivek formulationandevaluationofbiphasicreleasetabletcontainingdiclofenacbeads AT gonjariindrajeetd formulationandevaluationofbiphasicreleasetabletcontainingdiclofenacbeads AT usmaneavinash formulationandevaluationofbiphasicreleasetabletcontainingdiclofenacbeads
bdutipo_str	Repositorios
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Formulation and evaluation of biphasic release tablet containing diclofenac beads

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