Didanosine-loaded chitosan microspheres: optimization of fabrication process

Didanosine (ddI) is an important drug in the AIDS therapy. However, to overcome the instability of ddI in acid medium, the tablets have a large amount of buffer that can lead to side effects such as diarrhea and kidney problems. Microencapsulation of ddI can reduce the excessive use of buffers. In t...

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Autores principales: Silva, Classius F. da, Severino, Patrícia, Martins, Fernanda, Santana, Maria H. A.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8258
http://www.latamjpharm.org/resumenes/30/5/LAJOP_30_5_2_11.pdf
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