Extemporaneous oral preparations: an alternative for hospitalized children

The lack of pharmaceutical formulations proper for children favors the manipulation of extemporaneous oral preparations by hospital pharmacies. The study aimed to identify the medications reformulated by the pharmacy of Hospital de Clínicas de Porto Alegre, as well as the availability for use in ora...

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Detalles Bibliográficos
Autores principales:	Santos, Luciana dos, Heineck, Isabela
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia children; pediatric formulations; pharmaceutical preparations; unlicensed Hospitales Niño Preparaciones Farmacéuticas
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8249 http://www.latamjpharm.org/resumenes/30/5/LAJOP_30_5_2_2.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-8249
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia children; pediatric formulations; pharmaceutical preparations; unlicensed Hospitales Niño Preparaciones Farmacéuticas
spellingShingle	Farmacia children; pediatric formulations; pharmaceutical preparations; unlicensed Hospitales Niño Preparaciones Farmacéuticas Santos, Luciana dos Heineck, Isabela Extemporaneous oral preparations: an alternative for hospitalized children
topic_facet	Farmacia children; pediatric formulations; pharmaceutical preparations; unlicensed Hospitales Niño Preparaciones Farmacéuticas
description	The lack of pharmaceutical formulations proper for children favors the manipulation of extemporaneous oral preparations by hospital pharmacies. The study aimed to identify the medications reformulated by the pharmacy of Hospital de Clínicas de Porto Alegre, as well as the availability for use in oral liquid formulations on Pediatrics. The drugs were classified according to the criteria approved by the Food and Drug Administration; for that, the DrugDex-Micromedex® database was used, while the reformulated items were classified as unlicensed. 2026 medicines in the 342 prescriptions were analyzed, while 35 % were classified as off-label use and 14.9 % as not approved. Extemporaneous preparations were made for 3.8 % of the items, whereas 95 % showed stability studies in the literature. The drugs most frequent compounded in extemporaneous formulations drugs were baclofen (18.9 %), furosemide (10 %) and ursodeoxycholic acid (7.6 %). The results of this and other studies highlight the problem occasioned by the lack of pharmaceutical formulations appropriate for children.
format	Articulo Comunicacion
author	Santos, Luciana dos Heineck, Isabela
author_facet	Santos, Luciana dos Heineck, Isabela
author_sort	Santos, Luciana dos
title	Extemporaneous oral preparations: an alternative for hospitalized children
title_short	Extemporaneous oral preparations: an alternative for hospitalized children
title_full	Extemporaneous oral preparations: an alternative for hospitalized children
title_fullStr	Extemporaneous oral preparations: an alternative for hospitalized children
title_full_unstemmed	Extemporaneous oral preparations: an alternative for hospitalized children
title_sort	extemporaneous oral preparations: an alternative for hospitalized children
publishDate	2011
url	http://sedici.unlp.edu.ar/handle/10915/8249 http://www.latamjpharm.org/resumenes/30/5/LAJOP_30_5_2_2.pdf
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bdutipo_str	Repositorios
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Extemporaneous oral preparations: an alternative for hospitalized children

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