Time-dependent and concentration -dependent upregulation of carbamazepine efflux transporter: a preliminary assessment from salivary drug monitoring

The aim of the present study was to detect efflux transporter induction at salivary glands. Six healthy volunteers were involved. On the first day subjects received a single carbamazepine (CBZ) dose of 400 mg. Couples of salivary samples (first and second fraction, S1 and S2) were collected througho...

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Detalles Bibliográficos
Autores principales: Maldonado, Cecilia, Fagiolino, Pietro, Vázquez, Marta, Eiraldi, Rosa, Alvariza, Silvana, Bentancur, Camilo, Álvarez, Pablo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Glándulas Salivales
carbamazepine; efflux transporter induction; saliva drug levels
Anticonvulsivantes
Monitoreo de Drogas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8235
http://www.latamjpharm.org/resumenes/30/5/LAJOP_30_5_1_11.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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