Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture

The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legislation for the development of parameters concerning the characterization and qua...

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Autores principales: Alves, Mauro M. S., Mendes, Patrizia C., Vieira, Janaína G. P., Jardim, Mário A. G., Ozela, Eliana F., Costa, Roseane M.R., Barbosa, Wagner L.R., Silva Júnior, José O. C.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8219
http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_6.pdf
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id I19-R120-10915-8219
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Plantas Medicinales
Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization
Legislación Farmacéutica
Control de Calidad
Técnicas de Química Analítica
spellingShingle Farmacia
Plantas Medicinales
Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization
Legislación Farmacéutica
Control de Calidad
Técnicas de Química Analítica
Alves, Mauro M. S.
Mendes, Patrizia C.
Vieira, Janaína G. P.
Jardim, Mário A. G.
Ozela, Eliana F.
Costa, Roseane M.R.
Barbosa, Wagner L.R.
Silva Júnior, José O. C.
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
topic_facet Farmacia
Plantas Medicinales
Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization
Legislación Farmacéutica
Control de Calidad
Técnicas de Química Analítica
description The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legislation for the development of parameters concerning the characterization and quality control of leaf powder and tincture of Arrabidaea chica (H & B) Verlot. Known as cipó-pau (vinestick), carajeru, pariri, among others, it presents antifungal activity and is used in several diseases such as mycosis and ringworm. The physico-chemical characteristics of the plant drug. The phytochemical screening of the t inc tur e indi cat ed the pr e s enc e of r educ ing sugar s , anthocyanidins , anthocyanins , anthraquinones, steroids, triterpenoids, phenols, flavanonols, flavanols, flavanones, saponins and tannins catechists. HPLC chromatograms showed peaks at 275 nm and 290 nm, with Rt of 8.91 and 13.57 min, whose corresponding spectra showed absorption maxima which is characteristic of flavones and biflavonols -283 nm and 334 nm. Some metabolites found in the phytochemical screening and detected by HPLC may justify the popular use of A. chica as antimicrobial and antifungal medicine.
format Articulo
Comunicacion
author Alves, Mauro M. S.
Mendes, Patrizia C.
Vieira, Janaína G. P.
Jardim, Mário A. G.
Ozela, Eliana F.
Costa, Roseane M.R.
Barbosa, Wagner L.R.
Silva Júnior, José O. C.
author_facet Alves, Mauro M. S.
Mendes, Patrizia C.
Vieira, Janaína G. P.
Jardim, Mário A. G.
Ozela, Eliana F.
Costa, Roseane M.R.
Barbosa, Wagner L.R.
Silva Júnior, José O. C.
author_sort Alves, Mauro M. S.
title Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
title_short Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
title_full Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
title_fullStr Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
title_full_unstemmed Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
title_sort physicochemical and phytochemical control of arrabidaea chica (h. & b.) verlot leaf powder and standardized tincture
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8219
http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_6.pdf
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