Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture
The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legislation for the development of parameters concerning the characterization and qua...
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Autores principales: | , , , , , , , |
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Formato: | Articulo Comunicacion |
Lenguaje: | Inglés |
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2011
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8219 http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_6.pdf |
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I19-R120-10915-8219 |
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institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Farmacia Plantas Medicinales Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization Legislación Farmacéutica Control de Calidad Técnicas de Química Analítica |
spellingShingle |
Farmacia Plantas Medicinales Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization Legislación Farmacéutica Control de Calidad Técnicas de Química Analítica Alves, Mauro M. S. Mendes, Patrizia C. Vieira, Janaína G. P. Jardim, Mário A. G. Ozela, Eliana F. Costa, Roseane M.R. Barbosa, Wagner L.R. Silva Júnior, José O. C. Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
topic_facet |
Farmacia Plantas Medicinales Arrabidaea chica (H&B) Verlot.; herbal medicine quality control; tincture standardization Legislación Farmacéutica Control de Calidad Técnicas de Química Analítica |
description |
The quality control of herbal drugs and their intermediates is essential, especially when they are used as feedstock for medicine development. This study aimed at applying the methodologies established by Brazilian legislation for the development of parameters concerning the characterization and quality control of leaf powder and tincture of Arrabidaea chica (H & B) Verlot. Known as cipó-pau (vinestick), carajeru, pariri, among others, it presents antifungal activity and is used in several diseases such as mycosis and ringworm. The physico-chemical characteristics of the plant drug. The phytochemical screening of the t inc tur e indi cat ed the pr e s enc e of r educ ing sugar s , anthocyanidins , anthocyanins , anthraquinones, steroids, triterpenoids, phenols, flavanonols, flavanols, flavanones, saponins and tannins catechists. HPLC chromatograms showed peaks at 275 nm and 290 nm, with Rt of 8.91 and 13.57 min, whose corresponding spectra showed absorption maxima which is characteristic of flavones and biflavonols -283 nm and 334 nm. Some metabolites found in the phytochemical screening and detected by HPLC may justify the popular use of A. chica as antimicrobial and antifungal medicine. |
format |
Articulo Comunicacion |
author |
Alves, Mauro M. S. Mendes, Patrizia C. Vieira, Janaína G. P. Jardim, Mário A. G. Ozela, Eliana F. Costa, Roseane M.R. Barbosa, Wagner L.R. Silva Júnior, José O. C. |
author_facet |
Alves, Mauro M. S. Mendes, Patrizia C. Vieira, Janaína G. P. Jardim, Mário A. G. Ozela, Eliana F. Costa, Roseane M.R. Barbosa, Wagner L.R. Silva Júnior, José O. C. |
author_sort |
Alves, Mauro M. S. |
title |
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
title_short |
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
title_full |
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
title_fullStr |
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
title_full_unstemmed |
Physicochemical and phytochemical control of Arrabidaea chica (H. & B.) Verlot leaf powder and standardized tincture |
title_sort |
physicochemical and phytochemical control of arrabidaea chica (h. & b.) verlot leaf powder and standardized tincture |
publishDate |
2011 |
url |
http://sedici.unlp.edu.ar/handle/10915/8219 http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_6.pdf |
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