Laccase-based biosensor for determination of acetaminophen

The use of biosensors based on laccase is an interesting alternative for monitoring phenolic compounds in pharmaceutical and environmental analysis. The detection and determination of acetaminophen in pharmaceutical samples, using a biosensor with carbon paste modified with laccase is described. The...

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Detalles Bibliográficos
Autores principales: Cordeiro, Diogo D., Gil, Éric S.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
acetaminophen; biosensor; laccase
Enzimas
Técnicas y Procedimientos de Laboratorio
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8187
http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_13.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8187
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
acetaminophen; biosensor; laccase
Enzimas
Técnicas y Procedimientos de Laboratorio
spellingShingle Farmacia
acetaminophen; biosensor; laccase
Enzimas
Técnicas y Procedimientos de Laboratorio
Cordeiro, Diogo D.
Gil, Éric S.
Laccase-based biosensor for determination of acetaminophen
topic_facet Farmacia
acetaminophen; biosensor; laccase
Enzimas
Técnicas y Procedimientos de Laboratorio
description The use of biosensors based on laccase is an interesting alternative for monitoring phenolic compounds in pharmaceutical and environmental analysis. The detection and determination of acetaminophen in pharmaceutical samples, using a biosensor with carbon paste modified with laccase is described. The method showed good linearity (r = 0.9954) and low detection and quantification limits (2.4 x 10<sup>-6</sup> mol.L<sup>-1</sup> and 7.9 x 10<sup>-6</sup> mol.L<sup>-1</sup>, respectively). Furthermore, the proposed methodology using an enzyme electrode showed appropriated reproducibility and selectivity.
format Articulo
Comunicacion
author Cordeiro, Diogo D.
Gil, Éric S.
author_facet Cordeiro, Diogo D.
Gil, Éric S.
author_sort Cordeiro, Diogo D.
title Laccase-based biosensor for determination of acetaminophen
title_short Laccase-based biosensor for determination of acetaminophen
title_full Laccase-based biosensor for determination of acetaminophen
title_fullStr Laccase-based biosensor for determination of acetaminophen
title_full_unstemmed Laccase-based biosensor for determination of acetaminophen
title_sort laccase-based biosensor for determination of acetaminophen
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8187
http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_13.pdf
work_keys_str_mv AT cordeirodiogod laccasebasedbiosensorfordeterminationofacetaminophen
AT gilerics laccasebasedbiosensorfordeterminationofacetaminophen
bdutipo_str Repositorios
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