Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan
Studies were carried out on the rhizome of Lasia spinosa (L.). The petroleum ether, ethyl acetate and the methanolic extract revealed moderate activities against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans, Aspergillus niger and Vibrio parahemolyticus test organisms. T...
Guardado en:
| Autores principales: | , , , , , |
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| Formato: | Articulo Comunicacion |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8177 http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_2.pdf |
| Aporte de: |
| id |
I19-R120-10915-8177 |
|---|---|
| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Farmacia Raíces de la Planta antimicrobial activity; araceae; cytotoxicity; Lasia spinosa; meridinol Pruebas de Toxicidad |
| spellingShingle |
Farmacia Raíces de la Planta antimicrobial activity; araceae; cytotoxicity; Lasia spinosa; meridinol Pruebas de Toxicidad Alam, Fakrul Haque, Mozammel Sohrab, Hossain Monsur, Mohammad A. Hasan, Choudhury M. Ahmed, Nuruddin Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| topic_facet |
Farmacia Raíces de la Planta antimicrobial activity; araceae; cytotoxicity; Lasia spinosa; meridinol Pruebas de Toxicidad |
| description |
Studies were carried out on the rhizome of Lasia spinosa (L.). The petroleum ether, ethyl acetate and the methanolic extract revealed moderate activities against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans, Aspergillus niger and Vibrio parahemolyticus test organisms. The crude extracts and purified compound, meridinol (1) were screened for antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi by the disc diffusion method. The cytotoxic potential of the extractives and meridinol was also determined by using brine shrimp lethality bioassay, where the extractives demonstrated significant cytotoxic activities. The petroleum ether, ethyl acetate, methanol extracts, one column fraction and compound 1 demonstrated LC90 of 11.22 μg/ml, 12.3 μg/ml, 13.49 μg/ml, 11.57 μg/ml and 15.85 μg/ml, respectively. |
| format |
Articulo Comunicacion |
| author |
Alam, Fakrul Haque, Mozammel Sohrab, Hossain Monsur, Mohammad A. Hasan, Choudhury M. Ahmed, Nuruddin |
| author_facet |
Alam, Fakrul Haque, Mozammel Sohrab, Hossain Monsur, Mohammad A. Hasan, Choudhury M. Ahmed, Nuruddin |
| author_sort |
Alam, Fakrul |
| title |
Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| title_short |
Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| title_full |
Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| title_fullStr |
Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| title_full_unstemmed |
Antimicrobial and cytotoxic activity from Lasia spinosa and isolated lignan |
| title_sort |
antimicrobial and cytotoxic activity from lasia spinosa and isolated lignan |
| publishDate |
2011 |
| url |
http://sedici.unlp.edu.ar/handle/10915/8177 http://www.latamjpharm.org/resumenes/30/3/LAJOP_30_3_2_2.pdf |
| work_keys_str_mv |
AT alamfakrul antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan AT haquemozammel antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan AT sohrabhossain antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan AT monsurmohammada antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan AT hasanchoudhurym antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan AT ahmednuruddin antimicrobialandcytotoxicactivityfromlasiaspinosaandisolatedlignan |
| bdutipo_str |
Repositorios |
| _version_ |
1764820488392015875 |