Docking studies of few substituted 5-benzyl-2, 4-thiazolidinedione with PPAR-γ for antidiabetic activity

Docking studies of few substituted 5-benzyl-2, 4-thiazolidinedione moiety, which acts as peroxisome proliferator-activated receptor γ agonist was performed by using Glide v4.5. The docking studies reveal hydrogen bond formation to Thr241 with Gscore -7.22 and energy -62.2 kcal/mole. We found hydroge...

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Detalles Bibliográficos
Autores principales: Sonawane, Lalit V., Bari, Sanjaykumar B.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
docking; glide; PPAR-γ rosiglitazone; thiazolidinedione
Tiazoles
Técnicas de Química Analítica
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8155
http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_2_12.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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