Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice

Tephrosia purpurea L. (Leguminosae), commonly known as Unhali in Marathi is a copiously branched perennial herb. Traditionally the roots of this plant are used in the treatment of ulcer and colic pain. So the present work was undertaken to validate its use in the treatment of ulcerative colitis by...

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Detalles Bibliográficos
Autores principales:	Sonawane, Leena L., Nirmal, Sunil A., Rub, Ruksana A., Goswami, Dhirendra, Bhawar, Sanjay B., Dhasade, Vipul V., Sonawane, Sneha D.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2011
Materias:	Farmacia Extractos Vegetales Tephrosia purpurea; ulcerative colitis; myeloperoxidase; histopathology Técnicas y Procedimientos de Laboratorio Gastroenteritis
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/8154 http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_2_11.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia Extractos Vegetales Tephrosia purpurea; ulcerative colitis; myeloperoxidase; histopathology Técnicas y Procedimientos de Laboratorio Gastroenteritis
spellingShingle	Farmacia Extractos Vegetales Tephrosia purpurea; ulcerative colitis; myeloperoxidase; histopathology Técnicas y Procedimientos de Laboratorio Gastroenteritis Sonawane, Leena L. Nirmal, Sunil A. Rub, Ruksana A. Goswami, Dhirendra Bhawar, Sanjay B. Dhasade, Vipul V. Sonawane, Sneha D. Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
topic_facet	Farmacia Extractos Vegetales Tephrosia purpurea; ulcerative colitis; myeloperoxidase; histopathology Técnicas y Procedimientos de Laboratorio Gastroenteritis
description	Tephrosia purpurea L. (Leguminosae), commonly known as Unhali in Marathi is a copiously branched perennial herb. Traditionally the roots of this plant are used in the treatment of ulcer and colic pain. So the present work was undertaken to validate its use in the treatment of ulcerative colitis by using suitable scientific methods. Shade dried and coarsely powdered roots were subjected to successive extraction with ethanol and water. The dried extracts (100 and 200 mg/kg) were screened for ulcerative colitis using the method acetic acid induced ulcerative colitis in mice. Macroscopical study of the colon, level of myeloperoxidase in colon and histopathology of the colon tissue were studied for the assessment of the activity. Results showed that aqueous extract was significantly effective in the treatment of ulcerative colitis at dose of 200 mg/kg. It can be concluded that the polar constituents of T. purpurea L. may be useful in the treatment of ulcerative colitis.
format	Articulo Comunicacion
author	Sonawane, Leena L. Nirmal, Sunil A. Rub, Ruksana A. Goswami, Dhirendra Bhawar, Sanjay B. Dhasade, Vipul V. Sonawane, Sneha D.
author_facet	Sonawane, Leena L. Nirmal, Sunil A. Rub, Ruksana A. Goswami, Dhirendra Bhawar, Sanjay B. Dhasade, Vipul V. Sonawane, Sneha D.
author_sort	Sonawane, Leena L.
title	Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
title_short	Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
title_full	Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
title_fullStr	Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
title_full_unstemmed	Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice
title_sort	effect of tephrosia purpurea roots extracts on acetic acid induced colitis in mice
publishDate	2011
url	http://sedici.unlp.edu.ar/handle/10915/8154 http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_2_11.pdf
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Effect of Tephrosia purpurea roots extracts on acetic acid induced colitis in mice

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