Gastroretentive drug delivery system of captopril and hydrochlorothiazide bilayer tablet: formulation, optimization and in vivo evaluation
The purpose of the present study was to develop and optimize floating-bioadhesive bilayer gastroretentive drug delivery system (GRDDS) exhibiting a unique combination of floatation and bioadhesion to prolong residence in the stomach using captopril (CP) and hydrochlorothiazide (HCTZ) as a model d...
Guardado en:
| Autores principales: | Wadekar, Sharadchandra B., Kshirsagar, Sanjay J., Gupta, Sunil R., Shewale, Nitin S., Bhalekar, Mangesh R., Supe, Santosh |
|---|---|
| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8140 http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_1_16.pdf |
| Aporte de: |
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