Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters
Multiple drug administration increases chances of drug interaction, altering the responses of drugs either increasing or decreasing pharmacological effects, or generating a new pharmacological response. Generally drug interactions should be avoided, due to the possibility of poor or unexpected outco...
Guardado en:
| Autores principales: | , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
| Publicado: |
2011
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8128 http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_1_3.pdf |
| Aporte de: |
| id |
I19-R120-10915-8128 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Farmacia cumulative adverse effects; hematological and hepatic parameters Interacciones de Drogas Acciones Farmacológicas |
| spellingShingle |
Farmacia cumulative adverse effects; hematological and hepatic parameters Interacciones de Drogas Acciones Farmacológicas Afroz, Syeda Feroz, Zeeshan Khan, Rafeeq A. Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| topic_facet |
Farmacia cumulative adverse effects; hematological and hepatic parameters Interacciones de Drogas Acciones Farmacológicas |
| description |
Multiple drug administration increases chances of drug interaction, altering the responses of drugs either increasing or decreasing pharmacological effects, or generating a new pharmacological response. Generally drug interactions should be avoided, due to the possibility of poor or unexpected outcomes. The present study was designed to explore relatively safe combination that can be used in individuals with multiple disorders such as epilepsy, hypertension, arrhythmia and diabetes. The study was conducted in normal rabbits of either sex following administration of drugs for a period of 60 days; various biochemical tests were performed to assess their hepatic and hematological profile. Results of this study suggest that animals of group receiving amiodarone-glibenclamide-captopril-oxcarbazepine combination revealed comparatively more toxic effects than two other combinations. |
| format |
Articulo Articulo |
| author |
Afroz, Syeda Feroz, Zeeshan Khan, Rafeeq A. |
| author_facet |
Afroz, Syeda Feroz, Zeeshan Khan, Rafeeq A. |
| author_sort |
Afroz, Syeda |
| title |
Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| title_short |
Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| title_full |
Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| title_fullStr |
Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| title_full_unstemmed |
Adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| title_sort |
adverse effects of anti-epileptic, anti-hypertensive, anti-diabetic and anti-arrhythmic drugs on hematological and hepatic parameters |
| publishDate |
2011 |
| url |
http://sedici.unlp.edu.ar/handle/10915/8128 http://www.latamjpharm.org/resumenes/30/2/LAJOP_30_2_1_3.pdf |
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Repositorios |
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