Standardization of Caco-2 cell culture as in vitro model for intestinal permeability

The aim of this study was to find out the optimal experimental conditions for Caco-2 cell culture (time and density) and permeability assays (diffusion system and drug concentration) in order to study the in vitro drugs permeability as a predictive method for drug absorption across intestinal epit...

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Detalles Bibliográficos
Autores principales: Rodríguez, Yanina I., Abalos, Ivana S., Lozano, Verónica, Cereseto, Marina, Silberman, Nicolás G., Chiale, Carlos, Gruñeiro, Elena, Pesce, Guido
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Técnicas de Cultivo de Célula
atenolol; biopharmaceutics classification system; Caco-2; permeability
Permeabilidad
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8097
http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_5.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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